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  • Gas chromatography
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  • 1
    Electronic Resource
    Electronic Resource
    Springer
    Archives of toxicology 29 (1972), S. 325-330 
    ISSN: 1432-0738
    Keywords: Gas chromatography ; Carbon Monoxide ; Blood-Iron ; Gaschromatographie ; Kohlenmonoxid ; Blut-Eisen
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Description / Table of Contents: Zusammenfassung Es wird ein Verfahren zur Kohlenmonoxidbestimmung im Blut angegeben, das besonders für forensische Zwecke bei faulem oder stark denaturiertem Blut, aber auch für arbeitsmedizinische Probleme geeignet ist. Der gaschromatographische Nachweis des Kohlenmonoxids ist eindeutig. Der CO-Hb-Gehalt des Blutes errechnet sich aus der Eisenkonzentration der Probe und der festgestellten Kohlenmonoxidmenge. Die gegenüber spektralphotometrischen Untersuchungen längere Arbeitszeit wird durch die höhere Sicherheit und Beweisfähigkeit der Methode, insbesondere im Bereich geringer Konzentrationen, aufgewogen. An Brandleichen erhobene Befunde dürfen nur unter Berücksichtigung der Vorgeschichte interpretiert werden.
    Notes: Abstract A method for the analysis of carbon monoxide in blood is discussed; it is particularly suitable for forensic application using decayed or denaturated blood, and also for problems in industrial medicine. Gas chromatographic analysis of carbon monoxide gives reliable results. The content of CO-Hb is calculated from the iron concentration of the sample and the amount of carbon monoxide. This method takes longer than spectrophotometric examination, but is more accurate, particularly with low concentrations. Results in blood taken following death by burning can be interpreted only in the light of the history.
    Type of Medium: Electronic Resource
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  • 2
    Electronic Resource
    Electronic Resource
    Weinheim : Wiley-Blackwell
    Angewandte Chemie International Edition in English 11 (1972), S. 366-375 
    ISSN: 0570-0833
    Keywords: Gas chromatography ; Computer chemistry ; Chemistry ; General Chemistry
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Chemistry and Pharmacology
    Additional Material: 9 Ill.
    Type of Medium: Electronic Resource
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  • 3
    Electronic Resource
    Electronic Resource
    Weinheim : Wiley-Blackwell
    Angewandte Chemie International Edition in English 2 (1963), S. 515-523 
    ISSN: 0570-0833
    Keywords: Permethylation ; Carbohydrates ; Methylation ; Gas chromatography ; Chemistry ; General Chemistry
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Chemistry and Pharmacology
    Notes: Methylation of mono-, oligo-, and polysaccharides with methyl iodide/barium oxide or dimethyl sulfate/barium hydroxide in dimethyl sulfoxide as solvent rapidly leads to high degrees of methylation. Depending on the structure and solubility of the substrate, permethylation can be achieved either in one operation or by repetition of the same treatment. Procedures of permethylation of various carbohydrates are given. The methyl glycosides obtained on methanolysis can be separated and determined quantitatively by gas chromatography. The preparation of separating columns with minimum retention for this purpose is described. Pullulan was shown to have the structure of a completely linear polymer of maltotriose units connected by α-1→6-linkages. - In addition the gaschromatographic identification of methyl ethers of glucosamine and galactosamine is reported.
    Additional Material: 15 Ill.
    Type of Medium: Electronic Resource
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  • 4
    ISSN: 0570-0833
    Keywords: Radiocarbon ; Gas chromatography ; Trace analysis ; Chemistry ; General Chemistry
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Chemistry and Pharmacology
    Notes: In biochemical work with isotopic tracers, it is frequently advantageous to investigate samples in the gas phase. In this way, the selectivity of gas-chromatographic separating columns and the sensitivity of detectors can be utilized for both the detection of gas-chromatographic fractions and the determination of their radioactive portions. Conversion of materials separated by gas chromatography into a single standard chemical compound prior to measurement of the radioactivity is recommended. Methods suitable for 14C-labelled compounds can also be applied to those labelled with 3H or 35S.
    Additional Material: 8 Ill.
    Type of Medium: Electronic Resource
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  • 5
    ISSN: 0570-0833
    Keywords: Racemization ; Peptide synthesis ; Gas chromatography ; Chemistry ; General Chemistry
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Chemistry and Pharmacology
    Notes: It is shown that the methyl esters of many diastereoisomeric N-trifluoroacetyldipeptides can be separated by gas chromatography on Golay columns. This makes it possible for the first time to carry out accurate quantitative investigations of recemization occurring during peptide synthesis without resort to measurements of optical rotation or enzymatic cleavage, and witout having to isolate the peptides. Some well-known methods of forming peptides were examined using the synthesis of the methyl ester of carbobenzoxy-L-valyl-L-valine as an example. The synthesis of the methyl ester of N-trifluoroacetyl-L-valyl-L-valine was investigated as a model for the linking of peptides. The influence on racemization of numerous factors was determined. General conclusions could be drawn regarding peptide synthesis.
    Additional Material: 3 Ill.
    Type of Medium: Electronic Resource
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