ISSN:
1573-8221
Schlagwort(e):
human embryonic tissue
;
Rous fowl sarcoma virus
;
transformation
;
polyoma virus
Quelle:
Springer Online Journal Archives 1860-2000
Thema:
Biologie
,
Medizin
Notizen:
Abstract A line of human embryonic fibroblasts, transformed by Rous sarcoma virus (Schmidt-Ruppin strain) contained and produced Rous virus, as was shown by the complement fixation and immunofluorescent tests, by electron-microscopic investigation, and by the presence of an isotope peak in a sucrose gradient. By its biological properties the synthesized virus differed from the original Schmidt-Ruppin strain for, in particular, the range of cells sensitive to the virus and its protein membrane were changed. Similar data indicating a change in the biological properties of a virus produced in the tissue of an unnatural host also were obtained for polyoma virus, synthesized in human embryonic fibroblasts transformed by it.
Materialart:
Digitale Medien
URL:
http://dx.doi.org/10.1007/BF00801826
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