ISSN:
1741-0444
Keywords:
Activated carbon
;
Adsorption
;
Catalysis
;
Competitive adsorption
;
Haemoperfusion
;
Intraparticle diffusivity
Source:
Springer Online Journal Archives 1860-2000
Topics:
Biology
,
Chemistry and Pharmacology
,
Medicine
Notes:
Abstract Thein vitro measurement of adsorption isotherms and intraparticle diffusivities for three types of activated carbon and four exogenous and endogenous toxins is described. Complications due to the chemical breakdown of creatinine and paracetamol in the presence of activated carbon are discussed. Three methods are compared for the estimation of intraparticle diffusivity from the kinetic data. The simplest method is also used to reinterpret literature data comparing diffusivity values using plasma or HSA solution as opposed to buffer as the solvent. The adsorption isotherms and intraparticle diffusivities comprise the fundamental data used to validate the mass transfer model of a haemoperfusion column developed in Part 2.
Type of Medium:
Electronic Resource
URL:
http://dx.doi.org/10.1007/BF02442777
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