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  • 1990-1994  (3)
  • 1980-1984
  • 1960-1964
  • 1920-1924
  • 1990  (3)
  • Alkaloids
  • 1
    Electronic Resource
    Electronic Resource
    Microbial degradation of the morphine alkaloids: identification of morphinone as an intermediate in the metabolism of morphine by Pseudomonas putida M10 (1990)
    Springer
    Archives of microbiology 154 (1990), S. 465-470 
    Details
    ISSN: 1432-072X
    Keywords: Pseudomnas putida ; Morphine ; Codeine ; Codeinone ; Morphinone ; Alkaloids ; Morphine dehydrogenase
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology
    Notes: Abstract A strain of Pseudomonas putida was isolated by selective enrichment with morphine that was capable of utilising morphine as a primary source of carbon and energy for growth. Experiments with whole cells showed that both morphine and codeine, but not thebaine, could be utilised. A novel NADP-dependent dehydrogenase, morphine dehydrogenase, was purified from crude cell extracts and was shown to be capable of oxidising morphine and codeine to morphinone and codeinone, respectively. This NADP-dependent morphine dehydrogenase was not observed in any other species of pseudomonads examined and was quite distinct from the β-hydroxysteroid dehydrogenase found in Pseudomonas testosteroni, which had previously been shown to have activity against morphine.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00245229
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    Paper (German National Licenses)
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  • 2
    Electronic Resource
    Electronic Resource
    Fate of plant-derived secondary metabolites in three moth species (Syntomis mogadorensis, Syntomeida epilais, andCreatonotos transiens) (1990)
    Springer
    Journal of comparative physiology 160 (1990), S. 389-400 
    Details
    ISSN: 1432-136X
    Keywords: Lepidoptera ; Herbivores ; Resorption ; Cardenolides ; Alkaloids
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Medicine
    Notes: Summary Larvae of three moth species were compared with respect to strategies used to cope with secondary metabolites (allelochemicals) present in their diet.Syntomeida epilais is monophagous and accepted only oleander (which contains cardenolides, CG). CG were detected as stored products in the larvae and also in the faeces and exuviae. Pure CG (digoxin and gitoxin) which do not occur in oleander fed on oleander leaves were sequestered as the oleander CG.Syntomis mogadorensis is polyphagous: given a choice larvae avoided plants with a high load of allelochemicals. Upon shortage of preferred plants they ate a wide variety of plants which contain alkaloids, terpenes, or phenolics. Of these allelochemicals, alkaloids and CG were mainly recovered in the faeces and only minute fractions in the larvae.Creatonotos transiens larvae behaved similarly toSyntomis in terms of polyphagy and non-resorption. However, the larvae took up and stored pyrrolizidine alkaloids (PA) such as heliotrine selectively.Creatonotos is thus polyphagous (a generalist) but also a PA-specialist which exploits PA as defensive agents, as a morphogen for the male pheromone gland, and as a precursor for the male pheromone.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF01075670
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    Paper (German National Licenses)
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  • 3
    Electronic Resource
    Electronic Resource
    Natural product chemistry, 140. Synthesis of some new acridones (1990)
    Weinheim : Wiley-Blackwell
    Liebigs Annalen 1990 (1990), S. 1047-1049 
    Details
    ISSN: 0170-2041
    Keywords: Acridones ; Alkaloids ; Chemistry ; Organic Chemistry
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Chemistry and Pharmacology
    Notes: Methyl 6-amino-2,3-dimethoxybenzoate (6) which was obtained from 6-formyl-2,3-dimethoxybenzoic acid (1), was treated with phloroglucinol to give two new acridone alkaloids, 1,3,8-trihydroxy-7-methoxy-9-acridone (7) and 1,3-dihydroxy-7,8-dimethoxy-9-acridone (8). Methylation of 7 and 8 gave another four new acridone alkaloids, 1,8-dihydroxy-3,7-dimethoxy-9-acridone (9), 1,8-dihydroxy-3,7-dimethoxy-10-methyl-9-acridone (10), 1-hydroxy-3,7,8-trimethoxy-10-methyl-9-acridone (11) and 1,3,7,8-tetramethoxy-10-methyl-9-acridone (12).
    Additional Material: 1 Tab.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/jlac.1990199001189
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    Paper (German National Licenses)
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