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  • 1
    Electronic Resource
    Electronic Resource
    Microbial degradation of the morphine alkaloids: identification of morphinone as an intermediate in the metabolism of morphine by Pseudomonas putida M10 (1990)
    Springer
    Archives of microbiology 154 (1990), S. 465-470 
    Details
    ISSN: 1432-072X
    Keywords: Pseudomnas putida ; Morphine ; Codeine ; Codeinone ; Morphinone ; Alkaloids ; Morphine dehydrogenase
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology
    Notes: Abstract A strain of Pseudomonas putida was isolated by selective enrichment with morphine that was capable of utilising morphine as a primary source of carbon and energy for growth. Experiments with whole cells showed that both morphine and codeine, but not thebaine, could be utilised. A novel NADP-dependent dehydrogenase, morphine dehydrogenase, was purified from crude cell extracts and was shown to be capable of oxidising morphine and codeine to morphinone and codeinone, respectively. This NADP-dependent morphine dehydrogenase was not observed in any other species of pseudomonads examined and was quite distinct from the β-hydroxysteroid dehydrogenase found in Pseudomonas testosteroni, which had previously been shown to have activity against morphine.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00245229
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  • 2
    Electronic Resource
    Electronic Resource
    Occurrence of bombesin-like immunoreactivity in the brain of the cartilaginous fish,Scyliorhinus canicula (1990)
    Springer
    Cell & tissue research 259 (1990), S. 177-181 
    Details
    ISSN: 1432-0878
    Keywords: Bombesin-like peptide ; Immunocytochemistry ; Hypothalamus ; Neurosecretory ; Fibers ; Scyliorhinus canicula (Elasmobranchii)
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Medicine
    Notes: Summary The presence and distribution of bombesin-like material were investigated in the brain of the cartilaginous fishScyliorhinus canicula using conventional immunocytochemical techniques. Perikarya containing bombesin-like immunoreactivity were identified in the hypothalamus, within the magnocellular component of the preoptic nucleus. Some immunopositive elements appeared to be of cerebrospinal fluid-contacting type. Beaded immunoreactive fibers were seen crossing the ventral telencephalon and the whole hypothalamus. An important tract of fibers was found in the infundibular floor and in the median eminence, in close contact with the vascular system of the pituitary portal plexus. A moderate number of positive fibers innervated the habenular complex and the dorsal wall of the posterior tuberculum. These findings indicate that a neuropeptide strictly related to amphibian bombesin is located in specific hypothalamic neurons ofS. canicula. The distribution of the immunoreactive fibers and terminals suggests that, in fish, this peptide, may be involved in neuroendocrine and neuromodulator functions.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00571441
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  • 3
    Electronic Resource
    Electronic Resource
    SAXS experiments on gel-spun polyethylene fibers (1990)
    Springer
    Colloid & polymer science 268 (1990), S. 245-255 
    Details
    ISSN: 1435-1536
    Keywords: Fibers ; polyethylene ; gel-spinning ; smallanglex-rayscattering ; spinningconditions
    Source: Springer Online Journal Archives 1860-2000
    Topics: Chemistry and Pharmacology , Mechanical Engineering, Materials Science, Production Engineering, Mining and Metallurgy, Traffic Engineering, Precision Mechanics
    Notes: Abstract The properties of gel-spun polyethylene fibers hot-drawn to the maximum draw ratio depend on the spinning conditions. Different spinning conditions result in two types of structure in the paraffin oil containing fibers: an isotropic lamellar structure or a shish-kebab structure. Meridional SAXS experiments can identify the structure present. After extraction, these structures are still present but can be detected only in a more indirect way by SAXS experiments because of an excessive contribution of void scattering. During hot-drawing both structures are transformed into a more fibrillar structure. The shish-kebab structures can be drawn only to relatively low hot-draw ratios with an incomplete transformation of the lamellar overgrowth into the fibrils, as demonstrated by the presence of a meridional SAXS maximum/shoulder. This leads to relatively weak fibers. Lamellar structures can be drawn to high draw ratios by chain unfolding. A nearly complete transformation of the lamellae into fibrils is obtained and the fibers have excellent properties. The information about the morphology obtained by SAXS, DSC, WAXS, and SEM can be used to establish a relation between morphology and properties.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF01490249
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  • 4
    Electronic Resource
    Electronic Resource
    Fate of plant-derived secondary metabolites in three moth species (Syntomis mogadorensis, Syntomeida epilais, andCreatonotos transiens) (1990)
    Springer
    Journal of comparative physiology 160 (1990), S. 389-400 
    Details
    ISSN: 1432-136X
    Keywords: Lepidoptera ; Herbivores ; Resorption ; Cardenolides ; Alkaloids
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Medicine
    Notes: Summary Larvae of three moth species were compared with respect to strategies used to cope with secondary metabolites (allelochemicals) present in their diet.Syntomeida epilais is monophagous and accepted only oleander (which contains cardenolides, CG). CG were detected as stored products in the larvae and also in the faeces and exuviae. Pure CG (digoxin and gitoxin) which do not occur in oleander fed on oleander leaves were sequestered as the oleander CG.Syntomis mogadorensis is polyphagous: given a choice larvae avoided plants with a high load of allelochemicals. Upon shortage of preferred plants they ate a wide variety of plants which contain alkaloids, terpenes, or phenolics. Of these allelochemicals, alkaloids and CG were mainly recovered in the faeces and only minute fractions in the larvae.Creatonotos transiens larvae behaved similarly toSyntomis in terms of polyphagy and non-resorption. However, the larvae took up and stored pyrrolizidine alkaloids (PA) such as heliotrine selectively.Creatonotos is thus polyphagous (a generalist) but also a PA-specialist which exploits PA as defensive agents, as a morphogen for the male pheromone gland, and as a precursor for the male pheromone.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF01075670
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  • 5
    Electronic Resource
    Electronic Resource
    Natural product chemistry, 140. Synthesis of some new acridones (1990)
    Weinheim : Wiley-Blackwell
    Liebigs Annalen 1990 (1990), S. 1047-1049 
    Details
    ISSN: 0170-2041
    Keywords: Acridones ; Alkaloids ; Chemistry ; Organic Chemistry
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Chemistry and Pharmacology
    Notes: Methyl 6-amino-2,3-dimethoxybenzoate (6) which was obtained from 6-formyl-2,3-dimethoxybenzoic acid (1), was treated with phloroglucinol to give two new acridone alkaloids, 1,3,8-trihydroxy-7-methoxy-9-acridone (7) and 1,3-dihydroxy-7,8-dimethoxy-9-acridone (8). Methylation of 7 and 8 gave another four new acridone alkaloids, 1,8-dihydroxy-3,7-dimethoxy-9-acridone (9), 1,8-dihydroxy-3,7-dimethoxy-10-methyl-9-acridone (10), 1-hydroxy-3,7,8-trimethoxy-10-methyl-9-acridone (11) and 1,3,7,8-tetramethoxy-10-methyl-9-acridone (12).
    Additional Material: 1 Tab.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/jlac.1990199001189
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    Paper (German National Licenses)
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