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  • 2020-2024
  • 2015-2019
  • 1990-1994  (6)
  • 1890-1899
  • 1992  (6)
  • Orchestrierung
  • Software
  • 1
    Electronic Resource
    Electronic Resource
    Modelling amino acid metabolism (1992)
    Springer
    Amino acids 3 (1992), S. 1-23 
    Details
    ISSN: 1438-2199
    Keywords: Amino acids ; Computers ; Inborn errors of metabolism ; Models ; Protein synthesis ; Software ; Systems analysis ; Urea
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary This article briefly summarises various aspects of building a model, before reviewing some models of protein turnover, the metabolism of selected amino acids, and urea synthesis in human subjects. Some software for use in modelling is noted. An Appendix lists terms with descriptions and definitions, which are often employed in modelling.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00806006
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    Paper (German National Licenses)
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  • 2
    Electronic Resource
    Electronic Resource
    Quantitative morphology for biologists and computer scientists: I. Computer-aided tutorial for biological stereology (version 1.0) (1992)
    New York, NY [u.a.] : Wiley-Blackwell
    Microscopy Research and Technique 21 (1992), S. 338-346 
    Details
    ISSN: 1059-910X
    Keywords: Tutorial ; Electron microscopy ; Light microscopy ; Software ; Quantitative morphology ; Stereology ; Morphometry ; Simulations ; Terminology ; Data types ; Sampling ; Hierarchies ; Interpretation of data ; Bio-Matrix Project ; Life and Medical Sciences ; Cell & Developmental Biology
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Natural Sciences in General
    Notes: This paper describes a computer-aided tutorial for biological stereology. Stereology, a type of quantitative morphology, includes a collection of statistical methods that quantify the structural compartments that can be viewed in sections with light and electron microscopy. These methods provide volume, surface, length, shape, and number data, and help define the quantitative relationships among the structural compartments of biological hierarchies. Hierarchies, which connect structural data ranging in size from molecules to organs, serve as a central core to which the data of biological databases can be linked. The tutorial focuses on two objectives. It provides the user primarily interested in using quantitative morphology databases with background information, and offers a set of state-of-the-art tools to researchers wishing to use these methods in the laboratory. The main topics of the tutorial include: introduction to quantitative morphology, symbols/terms, data types, sampling, hierarchies, data interpretation, and utilities. The tutorial runs under the MS-DOS operating system and requires at least an IBM PC AT (or compatible), a color monitor (EGA, VGA), 540 KB of RAM, and 3 MB of hard disk space. © 1992 Wiley-Liss, Inc.
    Additional Material: 5 Ill.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/jemt.1070210409
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    Paper (German National Licenses)
    Fulltext
  • 3
    Electronic Resource
    Electronic Resource
    The microcomputer and image analysis in diagnostic pathology (1992)
    New York, NY [u.a.] : Wiley-Blackwell
    Microscopy Research and Technique 21 (1992), S. 292-299 
    Details
    ISSN: 1059-910X
    Keywords: Morphometry ; Histology ; Cytology ; Software ; Life and Medical Sciences ; Cell & Developmental Biology
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Natural Sciences in General
    Notes: This paper presents a snapshot view of the influence and direction of microcomputer technology for image analysis techniques in diagnostic pathology.Microcomputers have had considerable impact in bringing image analysis to wider application. Semi-automated tracing techniques are a simple means of providing objective data and assist in a wide range of diagnostic problems. From the common theme of reducing subjectivity in diagnostic assessment, an extensive body of research has accrued. Some studies have addressed the need for quality control for reliable, routine application.Video digitizer cards bring digital image analysis within the reach of laboratory budgets, providing powerful tools for investigation of a wide range of cellular and tissue features. The use of staining procedures compatible with quantitative evaluation has become equally important. As well as assisting scene segmentation, cytochemical and immunochemical staining techniques relate the data to biological processes.With the present state of the art, practical use of microcomputer based image analysis is impaired by limitations of information extraction and specimen throughput. Recent advances in colour video imaging provide an extra dimension in the analysis of multi-spectral stains. Improvements will also be felt with predictable increase in speed of microprocessors, and with single chip devices which deliver video rate processing. If the full potential of this hardware is realized, high-speed, routine analysis becomes feasible. In addition, a microcomputer imaging system can play host to companion functions, such as image archiving and transmission.With this outlook, the use of microcomputers for image analysis in diagnostic pathology is certain to increase. However, it is the software in both design and concept which ultimately governs the performance which can be achieved. Progress may be made by structured software techniques, by application of mathematical principles, or by use of expert systems for data or image interpretation. © 1992 Wiley-Liss, Inc.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/jemt.1070210406
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    Paper (German National Licenses)
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  • 4
    Electronic Resource
    Electronic Resource
    Biological stereology: History, present state, future directions (1992)
    New York, NY [u.a.] : Wiley-Blackwell
    Microscopy Research and Technique 21 (1992), S. 255-261 
    Details
    ISSN: 1059-910X
    Keywords: Sterology ; Morphometry ; Quantitative morphology ; Computers ; Software ; Tutorials ; Simulations ; Databases ; Bio-Matrix Project ; Life and Medical Sciences ; Cell & Developmental Biology
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Natural Sciences in General
    Notes: The development of a quantitative structural platform for experimental biology - extending across a hierarchy of sizes ranging from molecules to organisms - has been punctuated by a series of major achievements over the last 30 years. Stereology, a form of quantitative morphology, has contributed handsomely to this success. A personal view is presented highlighting key events in the development of biological stereology. We also examine stereology with a view toward future developments in biology and speculate how stereology might contribute to the new biological infrastructure currently being built with computers. © 1992 Wiley-Liss, Inc.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/jemt.1070210402
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    Paper (German National Licenses)
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  • 5
    Electronic Resource
    Electronic Resource
    Computer-assisted morphometry: Point, intersection, and profile counting and three-dimensional reconstruction (1992)
    New York, NY [u.a.] : Wiley-Blackwell
    Microscopy Research and Technique 21 (1992), S. 262-270 
    Details
    ISSN: 1059-910X
    Keywords: Stereology ; Software ; Coordinate geometry ; Volume density, Surface density ; Numerical density ; Serial sections ; Light microscopy ; Electron microscopy ; Life and Medical Sciences ; Cell & Developmental Biology
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Natural Sciences in General
    Notes: The use of computers in morphometry can involve (1) automated image analysis, semiautomated image analysis and point, intersection, intercept and profile counts of two-dimensional images on tissue sections with mathematical extrapolation to the third dimension, (2) direct measurement of volumes, surfaces, lengths, and curvature using x,y,z coordinates of serial sectioned images, or (3) stereologic techniques and serial sections which is a combination of 1 and 2 above. Automated and semiautomated image analysis are generally restricted to specimens that are characterized by differential contrast such as interalveolar septa in the lung or histochemically stained mucous granules in pulmonary epithelium. Point, intersection, and profile counts using hand-held, notebook PCs, portable PCs, or standard PCs and MS-DOS - based application programs are extremely efficient, precise, affordable, and convenient methods of quantitating average values of a population. When morphometric measurements of individual structures are required, computer-assisted three-dimensional reconstruction using x,y,z coordinates of the surface outline from serial sections is a tedious yet precise method. We describe a computer program that efficiently estimates mean caliper diameter, volume, and surface area with less than five percent error with five sections per structure. We also describe a program that does digital image subtraction on serial sections, superimposes digitally generated test systems on biological images, and accumulates point, intersection, and profile counts using a Macintosh II series computer. © 1992 Wiley-Liss, Inc.
    Additional Material: 3 Ill.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/jemt.1070210403
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    Paper (German National Licenses)
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  • 6
    Electronic Resource
    Electronic Resource
    VESTA - Ein Computerprogramm zur Berechnung thermischer Prozesse in Strömungsrohrapparaten (1992)
    Weinheim : Wiley-Blackwell
    Chemie Ingenieur Technik - CIT 64 (1992), S. 748-749 
    Details
    ISSN: 0009-286X
    Keywords: Computer ; Software ; thermische Prozesse ; Strömungsrohrapparate ; Simulation ; Chemistry ; Polymer and Materials Science
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Chemistry and Pharmacology , Process Engineering, Biotechnology, Nutrition Technology
    Additional Material: 2 Ill.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/cite.330640823
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    Paper (German National Licenses)
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