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  • 1990-1994  (4,244)
  • Engineering General  (3,144)
  • Genetics  (1,100)
  • 1
    Electronic Resource
    Electronic Resource
    A gene in the HLA class I region contributes to susceptibility to IDDM in the Finnish population (1994)
    Springer
    Diabetologia 37 (1994), S. 937-944 
    Details
    ISSN: 1432-0428
    Keywords: Genetics ; haplotype ; HLA-A ; HLA-DQ ; HLA-DR ; tumour necrosis factor ; diabetes mellitus
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary In Finland the haplotype A2, Cw1, B56, DR4, DQ8 is the third most common haplotype in insulin-dependent diabetic (IDDM) patients and has the highest haplotype-specific absolute risk for IDDM. Cw1, B56, DR4, DQ8 haplotypes containing HLA-A alleles other than A2 are infrequent in the population and are not associated with IDDM. Comparison of the A2 and non-A2 haplotypes at the DNA level showed that they were identical at HLA-B,-DR, and -DQ loci. Evidence that class I alleles confer susceptibility to IDDM was obtained from the two HLA-C, -B, -DR and -DQ haplotypes most frequently found in IDDM patients in Finland. A24, A3 and A2 on the Cw3, B62, DR4, DQ8 haplotype, and A28, A2 and A1 on the Cw7, B8, DR3, DQ2 were all found to be associated with IDDM. In Finland these seven haplotypes, including A2, Cw1, B56, DR4, DQ8, account for 33% of diabetic haplotypes and 10.3% of non-diabetic haplotypes (p〈0.00001). The contribution of the class I region to IDDM susceptibility was also apparent in those IDDM patients lacking the disease-predisposing class II alleles. Significantly more non-DR3/non-DR4 IDDM patients (47 of 55) possessed two of the IDDM-associated HLA-A alleles compared to non-DR3/non-DR4 control subjects (40 of 58; p=0.038). Moreover, IDDM patients confirmed by oligotyping as unable to form a ‘diabetes-susceptibility’ DQ heterodimer, tended to possess two diabetes-associated HLA-A alleles (12 of 13) compared to control subjects (12 of 20; p=0.056).
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00400951
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  • 2
    Electronic Resource
    Electronic Resource
    Mitochondrial gene defects in patients with NIDDM (1994)
    Springer
    Diabetologia 37 (1994), S. 372-376 
    Details
    ISSN: 1432-0428
    Keywords: Genetics ; diabetes mellitus ; mitochondria ; maternal ; deafness
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary Non-insulin-dependent diabetes mellitus (NIDDM) has a strong genetic component and maternal factors have recently been implicated in disease inheritance. The mitochondrial myopathies are a group of diseases which often show maternal inheritance as a result of mtDNA defects; some patients have impaired glucose tolerance. Occasional families with maternally inherited diabetes and deafness associated with a deletion or point mutation of mtDNA have been reported. To assess the importance of mitochondrial gene defects in NIDDM, 150 unrelated diabetic subjects from Wales, UK and 68 unrelated patients with diabetes and at least one affected sibling from England, UK were studied. Southern blot analysis did not show any large mtDNA deletions or duplications. One patient had a mutation in the mitochondrial tRNAleu(UUR) gene at bp 3243. This mutation is commonly associated with the syndrome of mitochondrial encephalomyopathy, lactic acidosis and stroke like episodes (MELAS). Study of this patient and his siblings showed a distinct form of late-onset diabetes associated with nerve deafness but no clinical features of the MELAS syndrome. No diabetic subject was shown to have the mtDNA mutation at position 8344 (tRNAlys) which has previously been described in the syndrome of mitochondrial encephalomyopathy and red-ragged fibres (MERRF). The role of other mitochondrial gene defects in diabetes and the pathophysiological basis of glucose intolerance in patients with the MELAS mutation requires further elucidation.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00408473
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  • 3
    Electronic Resource
    Electronic Resource
    Familial amyotrophic lateral sclerosis with a mutation in the Cu/Zn superoxide dismutase gene (1994)
    Springer
    Acta neuropathologica 88 (1994), S. 185-188 
    Details
    ISSN: 1432-0533
    Keywords: Amyotrophic lateral sclerosis ; Neuropathology ; Posterior column involvement ; Genetics ; Superoxide dismutase
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract Several missense mutations within exons 1, 2, 4 and 5 of the gene for Cu/Zn-binding superoxide dismutase (SOD1) have been discovered to be involved in the development of chromosome 21q-linked familial amyotrophic lateral sclerosis (FALS). We describe here an autopsied patient with FALS, in whom we have recently identified a novel missense mutation in exon 1 of the SOD1 gene. The neuropathological findings were compatible with those described previously in patients with FALS with posterior column involvement. This suggests that mutations of the SOD1 gene may be responsible for this form of FALS.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00294513
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  • 4
    Electronic Resource
    Electronic Resource
    Familial amyotrophic lateral sclerosis with a mutation in the Cu/Zn superoxide dismutase gene (1994)
    Springer
    Acta neuropathologica 88 (1994), S. 185-188 
    Details
    ISSN: 1432-0533
    Keywords: Key words: Amyotrophic lateral sclerosis ; Neuropathology ; Posterior column involvement ; Genetics ; Superoxide dismutase
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract Several missense mutations within exons 1, 2, 4 and 5 of the gene for Cu/Zn-binding superoxide dismutase (SOD1) have been discovered to be involved in the development of chromosome 21q-linked familial amyotrophic lateral sclerosis (FALS). We describe here an autopsied patient with FALS, in whom we have recently identified a novel missense mutation in exon 1 of the SOD1 gene. The neuropathological findings were compatible with those described previously in patients with FALS with posterior column involvement. This suggests that mutations of the SOD1 gene may be responsible for this form of FALS.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00294513
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  • 5
    Electronic Resource
    Electronic Resource
    Myotonic dystrophy and limb girdle muscular dystrophy in one family (1994)
    Springer
    Journal of molecular medicine 72 (1994), S. 409-413 
    Details
    ISSN: 1432-1440
    Keywords: Myotonic dystrophy ; Limb girdle muscular dystrophy ; Genetics
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract A family is reported in which a 29-year-old woman showed the clinical features of myotonic dystrophy while her 26-year-old brother presented with the clinical picture of limb girdle syndrome. In the affected female, direct genetic testing for the specific myotonic dystrophy mutation on chromosome 19 revealed abnormal expansion of a repeat unit containing the three nucleotides cytosine, thymine, and guanine (CTG) — typical for myotonic dystrophy — while her diseased brother displayed two normal alleles. This supports the hypothesis of the extremely rare occurrence of two clinically and genetically different myopathies in one family. Genetic analysis of six other family members showed that the father of the diseased siblings as well as all of his three brothers and sisters had a pathological CTG repeat expansion, and that the other two family members tested had a normal allelic pattern. The number of CTG repeats in the diseased women was approximately tenfold higher than in her asymptomatic relatives who revealed an abnormal allelic pattern. The increase in CTG repeats with transmission to a subsequent generation in this family was paralleled by a dramatic increase in the severity of myotonic dystrophy.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00252840
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  • 6
    Electronic Resource
    Electronic Resource
    Absence epilepsy of early childhood —genetic aspects (1994)
    Springer
    European journal of pediatrics 153 (1994), S. 372-377 
    Details
    ISSN: 1432-1076
    Keywords: Epilepsy ; Absences ; Genetics
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract Clinical and EEG family data of 140 cases with early childhood epilepsy with absences are presented. The aim of the study was to evaluate, whether the occurrence of generalized tonic clonic seizures (GTCS) as a presenting symptom might correlate with family data, i.e. whether there are indications of heterogeneity. One hundred and forty cases were selected from the epilepsy family data base of the Neuropaediatric Department. The selection parameter was epilepsy with absences manifesting between the 1 st and 5th year of age. The incidence of seizures was evaluated in siblings, parents and parents' siblings. EEG records were available from 103 parents and 106 siblings. The analysis supports the assumption of heterogeneity within early childhood absence epilepsy. Parents and their sibs of cases manifesting with GTCS had seizures twice as often than parents and their sibs in the non-GTCS group. In the affected relatives of the GTCS group early onset GTCS prevailed, whereas in the relatives of the non-GTCS group absences were found more frequently. The EEG of relatives showed elevated incidences of spikes and waves and photosensitivity in both groups, indicating common genetic factors. In parents of the non-GTCS group, however, EEG pathology was significantly more frequent than in parents of the GTCS group. Comparing EEG pathology in parents with seizure risk in siblings, evidence for maternal preponderance in transmission of the seizure liability was found. Mothers' EEG seems to be the best predictor of the seizure risk in probands' siblings. Early childhood epilepsy with absences can be regarded as an intermediate type, showing overlap with early onset GTCS and myoclonic astatic epilepsy on the one side and with childhood absence epilepsy on the other.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF01956423
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  • 7
    Electronic Resource
    Electronic Resource
    766 cases of oral cleft in Italy (1994)
    Springer
    European journal of epidemiology 10 (1994), S. 317-324 
    Details
    ISSN: 1573-7284
    Keywords: Epidemiology ; Genetics ; Oral clefts ; Registers
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract Epidemiological and genetic variables for oral clefts were analysed for the years 1981–1989 in a case-control study of congenital malformations in the Emilia Romagna, Veneto, and Friuli regions, and in the Trento and Bolzano hospitals. Birth prevalence for all cases of cleft lip with or without cleft palate (CL(P)) was 8.2 per 10,000 births, and that for cleft palate only (CP) was 6.1 per 10,000. Coexisting abnormalities were found in 23% of CL(P) cases and in 43% of CP. No clusters in time or space were detected. For isolated clefts, a predominance of males among CL(P) and of females among CP was found; epilepsy was the only maternal risk factor correlated with clefts, and an association between clefting and consanguinity was found. Empirical recurrence risks were calculated in both isolated CL(P) and CP.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF01719356
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  • 8
    Electronic Resource
    Electronic Resource
    Renal eicosanoids and blood pressure in genetically hypertensive rats of the lyon strain (1994)
    Springer
    Journal of biomedical science 1 (1994), S. 201-203 
    Details
    ISSN: 1423-0127
    Keywords: Hypertension ; Eicosanoid ; Rat ; Genetics ; Kidney
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Medicine
    Notes: Abstract The present paper reviews the evidence for a possible involvement of renal eicosanoids in the pathophysiology of high blood pressure in genetically hypertensive rats of the Lyon strain. Both in vivo and in vitro experiments suggest that an increased ability to synthesize the vasoconstrictor prostaglandin H2 and/or thromboxane A2 in renal vessels (1) acts as an autocrine amplifier of pressor agents and (2) may contribute to resetting the pressure natriuresis curve which is a prerequisite for the development and maintenance of hypertension.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF02253302
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  • 9
    Electronic Resource
    Electronic Resource
    Follow-up and family study of postpartum psychoses (1994)
    Springer
    European archives of psychiatry and clinical neuroscience 244 (1994), S. 138-140 
    Details
    ISSN: 1433-8491
    Keywords: Parity ; Genetics ; Diathesis-stress model
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract As part of a follow-up and family study of post-partum psychoses, this episode of illness being the first leading to psychiatric hospitalisation, patients with puerperal episodes (PE) and nonpuerperal episodes (NPE) of illness in the long-term course (n=79) were compared to patients with PE only (n=40). Few differences were found. Relatives of patients with PE only had a lower morbidity risk for functional psychoses than relatives of patients with PE and NPE. A favourable course of illness in the presence of a low genetic predisposition may be expected, according to the diathesis-stress model of functional psychoses.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF02191888
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  • 10
    Electronic Resource
    Electronic Resource
    Multiple sclerosis: genetic versus environmental aetiology: epidemiology in Israel updated (1994)
    Springer
    Journal of neurology 241 (1994), S. 341-346 
    Details
    ISSN: 1432-1459
    Keywords: Multiple sclerosis Epidemiology ; Immigrants Environment ; Genetics
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract The incidence and prevalence of multiple sclerosis (MS) were compared, controlling for age, in native-born Israelis of different origins and in immigrants to Israel. This comparison was carried out in two populations, countrywide and in Jerusalem. In the countrywide population, ascertainment was based mainly on hospitalizations; it included 252 patients who were native-born and 150 who had immigrated from Africa-Asia (AA immigrants). The 89 MS patients of Jerusalem also included patients diagnosed in outpatient clinics. In native-born Israelis whose father was born in Europe-America (I-EA), the incidence and prevalence of MS were found to be as high as or even higher than that found previously in immigrants from Europe-America. Among native-born Israelis whose father was born in Africa or Asia (I-AA), the yearly age-adjusted incidence and prevalence rates were found to be 1.4- to 1.8-fold higher than among AA immigrants, pointing to environmental factors. The incidence and prevalence rates in the I-EA were 1.2- to 1.6-fold higher than in the I-AA, pointing to genetic factors. These results seem to point to both environmental and genetic factors in the aetiology of MS. Further research is needed, however, to disentangle the genetic factors from possible environmental differences in the two ethnic groups.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00868444
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  • 11
    Electronic Resource
    Electronic Resource
    Clinical and genetic aspects of juvenile absence epilepsy (1994)
    Springer
    Journal of neurology 241 (1994), S. 487-491 
    Details
    ISSN: 1432-1459
    Keywords: Juvenile absence epilepsy ; Valproate ; Genetics
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract Fifteen patients aged 11–25 years (mean 15.37, SD 3.89) suffering from juvenile absence epilepsy are presented. Only 3 (20%) had absences (AS) as the only seizure type, 12 (80%) had associated generalized tonic-clinic seizures (GTCS) and in the remaining 3 with absences and GTCS there was also sporadic myoclonus. We found a higher frequency of AS in our patients by clinical history and video-EEG than has been previously reported. In our patients the mean age of onset in years was 11.4, SD 1.24 for AS, 13.12, SD 2.31 for GTCS and 12.5, SD 2.18 for myoclonus. The correct diagnosis was not made on referrals for any of the patients. It took an average of 3–5.5 years from the onset of the AS (range: 6–120 months) and 2 years from the occurrence of GTCS (average: 1–72 months) to make the correct diagnosis and institute proper treatment, which was valproic acid (VPA). The GTCS were controlled in all patients whereas AS continued in 6 (40%), but to a significantly lesser degree. The frequency and the duration of the GTCS before the start of VPA treatment seemed to have an adverse effect on AS control. We documented no circadian rhythm in either AS or the GTCS, except in 2 patients who had AS and GTCS mainly when they awoke in the morning. The sample size was too small to perform a proper genetic study, though a positive history of epilepsies of mixed types was obtained in 35.7% of the parents and the siblings of the probands.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00919710
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  • 12
    Electronic Resource
    Electronic Resource
    Mixed desmoplastic primitive neuroepithelial tumor of infancy: a light microscopic, immunocytochemical, ultrastructural and genetic study (1994)
    Springer
    Acta neuropathologica 89 (1994), S. 99-104 
    Details
    ISSN: 1432-0533
    Keywords: Key words     Primitive neuroepithelial tumor ; Desmoplastic small cell tumor ; Brain tumor of infancy ; Immunocytochemistry ; Genetics
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract      We describe a case of a desmoplastic brain tumor which was initially resected from the right fronto-temporal region in a 2 year-old boy. This nodular, calcified tumor was vascularized by the internal carotid artery and the middle meningeal artery branches. Grossly, it contained several mucoid cysts. Light microscopy showed cords or nests of small cuboidal cells surrounded by a loose connective tissue and desmoplasic areas containing fibers and spindle cells. The cuboidal cells expressed epithelial, neuronal and neuroendocrine markers. Some foci of spindle cells showed glial differentiation. The tumor recurred 16 months later and displayed some characteristics of the small cell neuroepithelial component, mitoses being conspicuous. Electron microscopy revealed undifferentiated clear cells, some containing neurosecretory granules. Karyotyping demonstrated the following formula: 〈 15 〉 46, t(8;11) (q13; q11). The chromosome 11 breakpoint was different from that described in Ewing's sarcoma. This isolated translocation has not been previously reported to our knowledge. These unusual features lead us to report this case and to discuss its pathogenesis.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/s004010050221
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  • 13
    Electronic Resource
    Electronic Resource
    Familial occurrence of discrete subaortic membrane (1994)
    Springer
    Pediatric cardiology 15 (1994), S. 198-200 
    Details
    ISSN: 1432-1971
    Keywords: Subaortic stenosis ; Congenital heart disease ; Genetics
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary The first case of multiple family members with discrete subaortic membrane and no other congenital defects is presented. One family member presents with findings suggesting a forme fruste of this disease. Increased surveillance of family members of individuals with discrete subaortic membrane is warranted, as the clinical findings of mild subaortic obstruction may be indistinguishable from those of an innocent flow murmur.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00800675
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  • 14
    Electronic Resource
    Electronic Resource
    Tricuspid atresia and annular hypoplasia: Report of a familial occurrence (1994)
    Springer
    Pediatric cardiology 15 (1994), S. 201-203 
    Details
    ISSN: 1432-1971
    Keywords: Tricuspid atresia ; Tricuspid hypoplasia ; Genetics
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary Occurrence of a similar cardiac malformation in multiple family members has been reported for many lesions. Neither tricuspid atresia nor tricuspid annular hypoplasia and tricuspid atresia and one case of tricuspid annular hypoplasia with an atrial septal defect in siblings. The findings in this family suggest an autosomal recessive pattern of inheritance for abnormal tricuspid valve morphogenesis.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00800676
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  • 15
    Electronic Resource
    Electronic Resource
    Molecular marker-facilitated studies in an elite maize population: I. Linkage analysis and determination of QTL for morphological traits (1994)
    Springer
    Theoretical and applied genetics 88 (1994), S. 7-16 
    Details
    ISSN: 1432-2242
    Keywords: Maize ; Restriction fragment length polymorphisms (RFLPs) ; Qualitative and quantitative inheritance ; Plant breeding ; Genetics
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology
    Notes: Abstract Restriction fragment length polymorphisms (RFLPs) and one morphological marker were used to investigate quantitative trait loci (QTL) for morphological and physiological traits evaluated on 150 F2∶3 maize (Zea mays L.) lines derived from the cross of elite U.S. Corn Belt inbreds Mo17 and H99. F2∶3 lines were grown in a replicated experiment and evaluated for plant and ear heights and flowering traits. QTL were identified for each trait, and genetic effects were determined. Estimated gene action for the flowering traits was predominantly overdominance. Both parents contributed toward increased values for anthesis and silk emergence. QTL for increased plant and ear heights were usually contributed by the taller parent, Mo17. Estimated gene action for these traits was mainly partial to overdominance. QTL for plant height were located in the vicinity of loci defined by alleles with qualitative effects on plant height.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00222387
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  • 16
    Electronic Resource
    Electronic Resource
    Chromosome assortment in Saccharum (1994)
    Springer
    Theoretical and applied genetics 89 (1994), S. 959-963 
    Details
    ISSN: 1432-2242
    Keywords: Sugarcane ; Polyploidy ; Genetics ; Evolution ; Breeding ; DNA markers ; Arbitrarily primed PCR ; RAPD markers
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology
    Notes: Abstract Recent work has revealed random chromosome pairing and assortment in Saccharum spontaneum L., the most widely distributed, and morphologically and cytologically variable of the species of Saccharum. This conclusion was based on the analysis of a segregating population from across between S. spontaneum ‘SES 208’ and a spontaneously-doubled haploid of itself, derived from anther culture. To determine whether polysomic inheritance is common in Saccharum and whether it is observed in a typical biparental cross, we studied chromosome pairing and assortment in 44 progeny of a cross between euploid, meiotically regular, 2n=80 forms of Saccharum officinarum ‘LA Purple’ and Saccharum robustum ‘ Mol 5829’. Papuan 2n=80 forms of S. robustum have been suggested as the immediate progenitor species for cultivated sugarcane (S. officinarum). A total of 738 loci in LA Purple and 720 loci in Mol 5829 were amplified and typed in the progeny by arbitrarily primed PCR using 45 primers. Fifty and 33 single-dose polymorphisms were identified in the S. officinarum and S. robustum genomes, respectively (χ 2 at 98%). Linkage analysis of single-dose polymorphisms in both genomes revealed linkages in repulsion and coupling phases. In the S. officinarum genome, a map hypothesis gave 7 linkage groups with 17 linked and 33 unlinked markers. Four of 13 pairwise linkages were in repulsion phase and 9 were in coupling phase. In the S. robustum genome, a map hypothesis gave 5 linkage groups, defined by 12 markers, with 21 markers unlinked, and 2 of 9 pairwise linkages were in repulsion phase. Therefore, complete polysomic inheritance was not observed in either species, suggesting that chromosomal behavior is different from that observed by linkage analysis of over 500 markers in the S. spontaneum map. Implications of this finding for evolution and breeding are discussed.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00224524
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  • 17
    Electronic Resource
    Electronic Resource
    Molecular-marker-facilitated investigation of host-plant response to Exserohilum turcicum in maize (Zea mays L.): components of resistance (1994)
    Springer
    Theoretical and applied genetics 88 (1994), S. 305-313 
    Details
    ISSN: 1432-2242
    Keywords: Breeding ; Helminthosporium turcicum ; RFLP ; QTLs ; Disease-resistance ; Genetics
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology
    Notes: Abstract RFLPs were used to investigate components of host-plant response to Exserohilum turcicum in 150 unselected F2∶3 lines of a B52/Mo17 maize population. Following inoculation with spore suspensions of the pathogen (race 0), components of disease development were measured and then quantitative trait mapping was performed to identify the location and effects of quantitative trait loci (QTLs) determining host-plant response. Components of interest were the average number of lesions per leaf, the average percent leaf tissue diseased (severity) and the average size of lesions (cm2). Based on a LOD threshold of 2.31 (P〈0.05), the number of lesions appears to be associated with QTLs on chromosomes 1S, 3L, 5S. Severity was associated with analogous regions and, in addition, QTLs on chromosomes 7L and 8L. Most QTLs, for either of these two components, involve additive gene action and partial dominance or overdominance. In contrast, lesion size was associated with QTLs on chromosomes 7L and 5L; recessive gene action may be involved at 7L.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00223637
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  • 18
    Electronic Resource
    Electronic Resource
    Resistance to potato leaf roll virus multiplication in potato is under major gene control (1994)
    Springer
    Theoretical and applied genetics 88 (1994), S. 754-758 
    Details
    ISSN: 1432-2242
    Keywords: Potato breeding ; Potato leaf roll virus ; Virus resistance ; Major gene resistance ; Genetics
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology
    Notes: Abstract The concentration of potato leaf roll virus (PLRV), as measured by a quantitative enzyme-linked immunosorbent assay, in the foliage of potato plants (Solanum tuberosum) of cv ‘Maris Piper’ with secondary infection was 2900 ng/g leaf, whereas in clones G7445(1) and G7032(5) it was 180 ng/g leaf and 120 ng/g leaf, respectively. To examine the genetic control of resistance to PLRV multiplication, reciprocal crosses were made between the susceptible cultivar ‘Maris Piper’ and the two resistant clones, and the three parents were selfed. Seedling progenies of these families were grown to generate tubers of individual genotypes (clones). Clonally propagated plants were graft-inoculated, and their daughter tubers were collected and used to grow plants with secondary infection in which PLRV concentration was estimated. The expression of resistance to PLRV multiplication had a bimodal distribution in progenies from crosses between ‘Maris Piper’ and either resistant clone, and also in progeny from selfing the resistant parents, with genotypes segregating into high and low virus titre groups. Only the progeny obtained from selfing ‘Maris Piper’ did not segregate, all genotypes being susceptible to PLRV multiplication. The pattern of segregation obtained from these progenies fits more closely with the genetical hypothesis that resistance to PLRV multiplication is controlled by two unlinked dominant complementary genes, both of which are required for resistance, than with the simpler hypothesis that resistance is conferred by a single dominant gene, as published previously.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF01253981
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  • 19
    Electronic Resource
    Electronic Resource
    Genetic analysis of tolerance for phosphorous deficiency in rice (Oryza sativa L.) (1994)
    Springer
    Theoretical and applied genetics 89 (1994), S. 313-317 
    Details
    ISSN: 1432-2242
    Keywords: Genetics ; Rice ; Phosphorousefficiency ; Diallel analysis
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology
    Notes: Abstract The inheritance of phosphorous (P) — deficiency tolerance in rice was investigated by a sevenparent diallel. The parent materials involved were four P-efficient (IR20, IR54, IR28, and Mahsuri), one moderately P-efficient (TN1), and two P-inefficient (IR31406333-1 and IR34686-179-1-2-1), genotypes. Relative tilering ability (RTA) under P-deficient and P-supplemented soil conditions was the parameter used in determining the tolerance level of the different genotypes. Diallel graph analysis revealed that tolerant parents have an excess of recessive genes, while moderate and susceptible parents possess more dominant genes. Genetic-component analysis suggested that both additive and dominance gene effects are involved in the inheritance of P-deficiency tolerance in rice. The trait exhibited over doiminance as confirmed by the graphical analysis. Narrow-sense heritability of the trait was moderate (0.50) and environmental effects were low. Both the general combining ability (GCA) and the specific combining ability (SCA) were significant, but GCA was more prevalent than SCA. Tolerant parents exhibited a high GCA whereas susceptibles have a very poor GCA, suggesting that tolerant parents were mostly enriched in additive genes and susceptible parents in non-additive genes. Crosses involving two high general combiners showed low SCA effects whereas crosses between poor general combiners manifested highly-significant SCA values.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00225160
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  • 20
    Electronic Resource
    Electronic Resource
    A linkage map of diploid Avena based on RFLP loci and a locus conferring resistance to nine isolates of Puccinia coronata var. ‘avenae’ (1994)
    Springer
    Theoretical and applied genetics 89 (1994), S. 831-837 
    Details
    ISSN: 1432-2242
    Keywords: Genetics ; Disease resistance ; Monocots
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology
    Notes: Abstract An F2 oat population was produced by crossing the diploid (n=7) species Avena strigosa (CI 3815) with A. wiestii (CI 1994), resistant and susceptible, respectively, to 40 isolates of Puccinia coronata, the causal agent of crown rust. Eighty-eight F2 individuals were used to construct an RFLP linkage map representing the A genome of cultivated hexaploid oat. Two hundred and eight RFLP loci have been placed into 10 linkage groups. This map covers 2416 cM, with an average of 12 cM between RFLP loci. Eighty-eight F3 lines, derived from F2 individuals used to construct the map, were screened for resistance to 9 isolates of P. coronata. One locus, Pca, was found to confer a dominant resistance phenotype to isolates 203, 258, 263, 264B, 290, 298, 325A, and 345. Pca also conferred resistance to isolate 276; however, an unlinked second gene may also be involved.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00224505
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  • 21
    Electronic Resource
    Electronic Resource
    Genetic analysis of a polyembryonic mutant in rye (1994)
    Springer
    Sexual plant reproduction 7 (1994), S. 290-296 
    Details
    ISSN: 1432-2145
    Keywords: Secale cereale ; Polyembryony ; Chromosome mosaics ; Rye ; Genetics
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology
    Notes: Abstract We have obtained one plant regenerated from rye tissue culture which showed a high percentage of polyembryonic seeds in its progeny. The mutation inducing the development of extra embryos is also influencing erroneous cell division, mitosis and meiosis. The genetic analysis indicated that the aptitude for polyembryonic seed formation is a heritable trait controlled by a dominant gene. However, for expression of the phenotype the female parent should have a specific cytoplasm.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00227712
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  • 22
    Electronic Resource
    Electronic Resource
    Genetic ecology: A new interdisciplinary science, fundamental for evolution, biodiversity and biosafety evaluations (1994)
    Springer
    Cellular and molecular life sciences 50 (1994), S. 429-437 
    Details
    ISSN: 1420-9071
    Keywords: Genetics ; ecology ; DNA-transfer ; conjugation ; transformation ; transduction ; transposons ; dormant cells ; epilithon ; microbial colonisation ; symbiosis ; virus resistance ; biosafety ; release of genes ; insults to humanity ; evolution ; biodiversity
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Medicine
    Notes: Abstract Genetic ecology is the extension of our modern knowledge in molecular genetics to studies of viability, gene expression and gene movements in natural environments like soils, aquifers and digestive tracts. In such milieux, the horizontal transfer of plasmid-borne genes between phylogenetically distant species has already been found to be much more frequent than had been expected from laboratory experience. For the study of exchanges involving chromosomally-located genes, more has to be learned about the behaviour of transposons in such environments. The results expected from studies in genetic ecology are relevant for considerations of evolution, biodiversity and biosafety. The role of this new field of research in restoring popular confidence in science and in its biotechnological applications is stressed.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF01920741
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  • 23
    Electronic Resource
    Electronic Resource
    Use of doxorubicin and dacarbazine for the management of unresectable intra-abdominal desmoid tumors in Gardner's syndrome (1994)
    Springer
    Diseases of the colon & rectum 37 (1994), S. 260-267 
    Details
    ISSN: 1530-0358
    Keywords: Desmoids ; Genetics ; Chemotherapy
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract PURPOSE: The aim of this study was to describe the natural history and management of surgically unresectable intra-abdominal desmoid tumors in two patients with Gardner's syndrome from two unrelated families, where each had failed on conventional therapy. METHODS: Two patients with Gardner's syndrome were placed on a chemotherapy regimen which included doxorubicin (90 mg/m2) and dacarbazine (900 mg/m2) in divided doses over four days of continuous infusion. Their progress on chemotherapy was assessed by abdominal computerized tomography and laparoscopy. RESULTS: The computerized abdominal tomography scans proved difficult to interpret because of adhesions and matted small bowel resulting from the patients original colectomies. These findings made it difficult to differentiate postoperative changes from residual desmoid tumor. Second-look laparotomy in such patients was contraindicated as this may predispose to further desmoid production. Laparoscopy disclosed a complete response to this chemotherapy. Nevertheless, we had an iatrogenic small bowel perforation in one of these patients. Each patient showed a complete response to chemotherapy. CONCLUSION: Surgical resection remains the first-line treatment of intra-abdominal desmoid tumors. However, doxorubicin/ dacarbazine chemotherapy on a clinical trial basis may be indicated in patients whose intra-abdominal desmoid is unresectable, or who have failed to respond to treatment with hormones (tamoxifen, Toremifene), steroids (prednisone), and nonsteroidal anti-inflammatory agents (Clinoril®; Merck & Co., Inc., West Point, PA).
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF02048164
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  • 24
    Electronic Resource
    Electronic Resource
    HLA class II genes and antibodies against recombinant U1-nRNP proteins in patients with systemic lupus erythematosus (1994)
    Springer
    Rheumatology international 14 (1994), S. 63-69 
    Details
    ISSN: 1437-160X
    Keywords: Systemic lupus erythematosus ; Recombinant U1-nRNP proteins ; Genetics
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract To investigate a possible involvement of HLA-class II alleles in the genetic predisposition for the formation of anti-U1-nRNP antibody in systemic lupus erythematosus (SLE), genomic DNA of 178 patients was typed for the DRB1, DQA1 and DQB1 alleles using a polymerase chain reaction (PCR) and non-radioactive-oligonucleotide typing. Antibodies against recombinant U1-nRNP proteins (U1-A- U1-C-and 70K-protein) were determined by ELISA. Anti-U1-C antibody was found in 26 (14.7%), anti-U1-A in 34 (19.2%) and anti-70K in 17 (9.6%) patients. A joint occurrence was observed for these antibodies against the recombinant U1-nRNP proteins: anti-U1-C and anti-U1-A antibodies occurred together more frequently than alone and than together with anti-U1-70K antibodies. The frequency of DRB1 * 04 was slightly increased in the patients with anti-U1-C as compared to the patients without anti-U1-C (P〈0.05, Pcorr=n.s., RR=2.4). The DQA1 * 0301 allele, which is in linkage disequilibrium with DRB1 * 04, is found more frequently in anti-U1-C-positive than in antibody-negative patients. The DQB1 * 0303 allele, detected in 12 of 176 SLE patients, was absent in the patients with any of the antibodies against the U1-nRNP proteins. All these deviations may be due to chance alone. We concluded that the presence of antibodies against recombinant U1-nRNP proteins was not significantly associated with any HLA DRB1, DQA1 and DQB1 allele in our group of SLE patients.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00300249
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  • 25
    Electronic Resource
    Electronic Resource
    Genetics of alcoholism: Role of the endogenous opioid system (1994)
    Springer
    Metabolic brain disease 9 (1994), S. 105-131 
    Details
    ISSN: 1573-7365
    Keywords: Alcoholism ; Genetics ; Endorphins ; Enkephalins ; Dynorphins ; Opioid ; Receptors
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract At the present time alcoholism is recognized as a metabolic disease exhibiting the clinical features of craving for alcohol, loss of control over drinking, tolerance and physical dependence on alcohol, while both epidemiological and experimental studies have demonstrated that genetic factors may be important in determining whether an individual has a high or low vulnerability to develop alcoholism. Evidence also indicates that alcoholism is not characterized by a single gene single allele inheritance. Instead it seems that multiple genes and environmental factors interact to increase or decrease an individual's vulnerability to become an alcoholic. Current research is aimed at investigating whether certain behavioral, physiological and biochemical markers are highly associated with the incidence of alcoholism. Among the biochemical markers currently under investigation is the endogenous opioid system and its implication in mediating the reinforcing effects of ethanol. It is the objective of this manuscript to review current research on: (a) the interactions of ethanol with the endogenous opioid system at the molecular level; (b) the existence of genetically determined differences in the response of the endogenous opioid system to ethanol between subjects at high and low risk for excessive ethanol consumption, as well as between lines of animals showing preference or aversion for ethanol solutions; (c) the decrease of alcohol consumption following pretreatment with opioid antagonists; and (d) the possible use of specific opioid receptor antagonists together with behavioral therapy to modify drinking behavior, to control craving and to prevent relapse.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF01999765
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  • 26
    Electronic Resource
    Electronic Resource
    Expression of a reporter gene is reduced by a ribozyme in transgenic plants (1994)
    Springer
    Molecular genetics and genomics 245 (1994), S. 465-470 
    Details
    ISSN: 1617-4623
    Keywords: Gene regulation ; Ribozyme ; npt-gene ; Transgenic tobacco ; Genetics
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology
    Notes: Abstract A chimeric gene encoding a ribozyme under the control of the cauliflower mosaic virus (CaMV) 35S promoter was introduced into transgenic tobacco plants. In vivo activity of this ribozyme, which was designed to cleave npt mRNA, was previously demonstrated by transient expression assays in plant protoplasts. The ribozyme gene was transferred into transgenic tobacco plants expressing an rbcS-npt chimeric gene as an indicator. Five double transformants out of sixteen exhibited a reduction in the amount of active NPT enzyme. To measure the amount of ribozyme produced, in the absence of its target, the ribozyme and target genes were separated by genetic segregation. The steady-state concentrations of ribozyme and target RNA were shown to be similar in the resulting single transformants. Direct evidence for a correlation between reduced npt gene expression and ribozyme expression was provided by crossing a plant containing only the ribozyme gene with a transgenic plant expressing the npt gene under control of the 35S promoter, i.e. the same promoter used to direct ribozyme expression. The expression of npt was reduced in all progeny containing both transgenes. Both steady-state levels of npt mRNA and amounts of active NPT enzyme are decreased. In addition, our data indicate that, at least in stable transformants, a large excess of ribozyme over target is not a prerequisite for achieving a significant reduction in target gene expression.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00302259
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  • 27
    Electronic Resource
    Electronic Resource
    p-version least squares finite element formulation for two-dimensional, incompressible, non-Newtonian isothermal and non-isothermal fluid flow (1994)
    Chichester : Wiley-Blackwell
    International Journal for Numerical Methods in Fluids 18 (1994), S. 127-162 
    Details
    ISSN: 0271-2091
    Keywords: Least squares ; Finite element ; p-version ; Error functional ; Power-law-fluid ; Non-isothermal ; Degrees of freedom ; p-convergence ; Hierarchial ; Newton's method ; Line search ; Engineering ; Engineering General
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Mechanical Engineering, Materials Science, Production Engineering, Mining and Metallurgy, Traffic Engineering, Precision Mechanics
    Notes: This paper presents a p- version least squares finite element formulation (LSFEF) for two-dimensional, incompressible, non-Newtonian fluid flow under isothermal and non-isothermal conditions. The dimensionless forms of the diffential equations describing the fluid motion and heat transfer are cast into a set of first-order differential equations using non-Newtonian stresses and heat fluxes as auxiliary variables. The velocities, pressure and temperature as well as the stresses and heat fluxes are interpolated using equal-order, C0-continuous, p-version hierarchical approximation functions. The application of least squares minimization to the set of coupled first-order non-linear partial differential equations results in finding a solution vector {δ} which makes the partial derivatives of the error functional with respect to {δ} a null vector. This is accomplished by using Newton's method with a line search.The paper presents the implementation of a power-law model for the non-Newtonian Viscosity. For the non-isothermal case the fluid properties are considered to be a function of temperature. Three numerical examples (fully developed flow between parallel plates, symmetric sudden expansion and lid-driven cavity) are presented for isothermal power-law fluid flow. The Couette shear flow problem and the 4:1 symmetric sudden expansion are used to present numerical results for non-isothermal power-law fluid flow. The numerical examples demonstrate the convergence characteristics and accuracy of the formulation.
    Additional Material: 31 Ill.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/fld.1650180202
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  • 28
    Electronic Resource
    Electronic Resource
    Masthead (1994)
    Chichester : Wiley-Blackwell
    International Journal for Numerical Methods in Fluids 18 (1994) 
    Details
    ISSN: 0271-2091
    Keywords: Engineering ; Engineering General
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Mechanical Engineering, Materials Science, Production Engineering, Mining and Metallurgy, Traffic Engineering, Precision Mechanics
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/fld.1650180301
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  • 29
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    Electronic Resource
    New numerical method for partial differential equations. 1: Application to the diffusion equation (1994)
    Chichester : Wiley-Blackwell
    International Journal for Numerical Methods in Fluids 18 (1994), S. 257-271 
    Details
    ISSN: 0271-2091
    Keywords: Engineering ; Engineering General
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Mechanical Engineering, Materials Science, Production Engineering, Mining and Metallurgy, Traffic Engineering, Precision Mechanics
    Notes: In this paper a new, highly accurate method called PH is presented for the numerical integration of partial differential equations. The method is applied for the solution of the one-dimensional diffusion equation. Upon integrating the equation within a subdomain of space and time using the prismoidal approximation, a three-point implicit scheme is obtained with a truncation error of order O(k4, h6), where k and h represent the time and space steps respectively. The method is stable under the condition s = αk/h2 ≤ S(δ), where the function S(δ) increases as the parameter δ decreases from 1/12 to negative values. In practice the method behaves as unconditionally stable upon choosing an appropriate value for δ. A new formula is also adopted for the implementation of a Neumann boundary condition, introducing a truncation error of order O(h4). Numerical solutions are obtained incorporating Dirichlet and Neumann boundary conditions. The results prove that our method is far more accurate than any other-implicit or explicit method.
    Additional Material: 2 Ill.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/fld.1650180303
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  • 30
    Electronic Resource
    Electronic Resource
    Conference diary (1994)
    Chichester : Wiley-Blackwell
    International Journal for Numerical Methods in Fluids 18 (1994), S. 333-335 
    Details
    ISSN: 0271-2091
    Keywords: Engineering ; Engineering General
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Mechanical Engineering, Materials Science, Production Engineering, Mining and Metallurgy, Traffic Engineering, Precision Mechanics
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/fld.1650180307
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  • 31
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    Electronic Resource
    Editorial (1994)
    Chichester : Wiley-Blackwell
    International Journal for Numerical Methods in Fluids 18 (1994), S. iii 
    Details
    ISSN: 0271-2091
    Keywords: Engineering ; Engineering General
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Mechanical Engineering, Materials Science, Production Engineering, Mining and Metallurgy, Traffic Engineering, Precision Mechanics
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/fld.1650180402
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  • 32
    Electronic Resource
    Electronic Resource
    Unstructured volume-agglomeration MG: Solution of the Poisson equation (1994)
    Chichester : Wiley-Blackwell
    International Journal for Numerical Methods in Fluids 18 (1994), S. 27-42 
    Details
    ISSN: 0271-2091
    Keywords: Engineering ; Engineering General
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Mechanical Engineering, Materials Science, Production Engineering, Mining and Metallurgy, Traffic Engineering, Precision Mechanics
    Notes: We are interested in solving second-order PDEs with multigrid and unstructured meshes. The multigrid strategy we present here is adapted from the generalized finite volume agglomeration multigrid algorithm we have developed recently for the solution of the Euler equations. We now focus on Poisson's equation. A strategy is defined by introducing a correction factor for the diffusive terms, and some illustrating results are given.
    Additional Material: 8 Ill.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/fld.1650180103
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  • 33
    Electronic Resource
    Electronic Resource
    p-version least squares finite element formulation for two-dimensional, incompressible fluid flow (1994)
    Chichester : Wiley-Blackwell
    International Journal for Numerical Methods in Fluids 18 (1994), S. 43-69 
    Details
    ISSN: 0271-2091
    Keywords: Least squares ; Finite element ; p-version ; Error functional ; Degrees of freedom ; p-convergence ; Newton's method ; Line search ; Navier-Stokes ; Hierarchical ; Driven cavity ; Asymmetric expansion ; Engineering ; Engineering General
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Mechanical Engineering, Materials Science, Production Engineering, Mining and Metallurgy, Traffic Engineering, Precision Mechanics
    Notes: A p-version least squares finite element formulation for non-linear problems is applied to the problem of steady, two-dimensional, incompressible fluid flow. The Navier-Stokes equations are cast as a set of first-order equations involving viscous stresses as auxiliary variables. Both the primary and auxiliary variables are interpolated using equal-order C0 continuity, p-version hierarchical approximation functions. The least squares functional (or error functional) is constructed using the system of coupled first-order non-linear partial differential equations without linearization, approximations or assumptions. The minimization of this least squares error functional results in finding a solution vector {δ} for which the partial derivative of the error functional (integrated sum of squares of the errors resulting from individual equations for the entire discretization) with respect to the nodal degrees of freedom {δ} becomes zero. This is accomplished by using Newton's method with a line search. Numerical examples are presented to demonstrate the convergence characteristics and accuracy of the method.
    Additional Material: 23 Ill.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/fld.1650180104
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  • 34
    Electronic Resource
    Electronic Resource
    Conference diary (1994)
    Chichester : Wiley-Blackwell
    International Journal for Numerical Methods in Fluids 18 (1994), S. 543-544 
    Details
    ISSN: 0271-2091
    Keywords: Engineering ; Engineering General
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Mechanical Engineering, Materials Science, Production Engineering, Mining and Metallurgy, Traffic Engineering, Precision Mechanics
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/fld.1650180508
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  • 35
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    Electronic Resource
    A vertex-centred finite volume method with shock detection (1994)
    Chichester : Wiley-Blackwell
    International Journal for Numerical Methods in Fluids 18 (1994), S. 605-625 
    Details
    ISSN: 0271-2091
    Keywords: Vertex-centred ; Finite volume ; Multigrid ; Navier-Stokes ; Shock detection ; Turbulence ; Engineering ; Engineering General
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Mechanical Engineering, Materials Science, Production Engineering, Mining and Metallurgy, Traffic Engineering, Precision Mechanics
    Notes: This paper introduces a vertex-centred finite volume method for compressible viscous flow incorporating a new shock detection procedure. The discretization is designed to be robust and accurate on the highly stretched and curved meshes necessary for resolving turbulent boundary layers around the leading edge of an aerofoil. Details of the method are described for two-dimensional problems and the natural extension of three-dimensional multiblock meshes is discussed. The shock detection procedure is used to limit the range of the shock-capturing dissipation specifically to regions containing shocks. For transonic turbulent flow this is shown to improve the boundary layer representation significantly.
    Additional Material: 15 Ill.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/fld.1650180605
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  • 36
    Electronic Resource
    Electronic Resource
    Masthead (1994)
    Chichester : Wiley-Blackwell
    International Journal for Numerical Methods in Fluids 18 (1994) 
    Details
    ISSN: 0271-2091
    Keywords: Engineering ; Engineering General
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Mechanical Engineering, Materials Science, Production Engineering, Mining and Metallurgy, Traffic Engineering, Precision Mechanics
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/fld.1650180701
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  • 37
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    Electronic Resource
    A net inflow method for incompressible viscous flow with moving free surface (1994)
    Chichester : Wiley-Blackwell
    International Journal for Numerical Methods in Fluids 18 (1994), S. 669-694 
    Details
    ISSN: 0271-2091
    Keywords: Free surface ; Finite element ; Viscous flow ; Engineering ; Engineering General
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Mechanical Engineering, Materials Science, Production Engineering, Mining and Metallurgy, Traffic Engineering, Precision Mechanics
    Notes: A new finite element procedure called the net inflow method has been developed to simulate time-dependent incompressible viscous flow including moving free surfaces and inertial effects. As a fixed mesh approach with triangular element, the net inflow method can be used to analyse the free surface flow in both regular and irregular domains. Most of the empty elements are excluded from the computational domain, which is adjusted successively to cover the entire region occupied by the liquid. The volume of liquid in a control volume is updated by integrating the net inflow of liquid during each iteration. No additional kinetic equation or material marker needs to be considered. The pressure on the free surface and in the liquid region can be solved explicitly with the continuity equation or implicitly by using the penalty function method. The radial planar free surface flow near a 2D point source and the dam-breaking problem on either a dry bed or a still liquid have been analysed and presented in this paper. The predictions agree very well with available analytical solutions, experimental measurements and/or other numerical results.
    Additional Material: 23 Ill.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/fld.1650180704
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  • 38
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    Generalized integral transform solution for boundary layer flow over a sphere (1994)
    Chichester : Wiley-Blackwell
    International Journal for Numerical Methods in Fluids 18 (1994), S. 721-731 
    Details
    ISSN: 0271-2091
    Keywords: Generalized integral transform technique ; Boundary layer ; Sphere ; Engineering ; Engineering General
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Mechanical Engineering, Materials Science, Production Engineering, Mining and Metallurgy, Traffic Engineering, Precision Mechanics
    Notes: The generalized integral transform technique is applied to the boundary layer equations for flow over a sphere in their primitive variables. Even though a diffusion-based eigenvalue problem is used, the velocity profile, shear stress and separation point have been calculated with high accuracy. Low-order approximations are shown to be accurate near the surface and the predictions of the separation point is very good. Comparison with finite difference results shows the better convergence behaviour of the integral transform method.
    Additional Material: 4 Ill.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/fld.1650180802
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  • 39
    Electronic Resource
    Electronic Resource
    Masthead (1994)
    Chichester : Wiley-Blackwell
    International Journal for Numerical Methods in Fluids 18 (1994) 
    Details
    ISSN: 0271-2091
    Keywords: Engineering ; Engineering General
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Mechanical Engineering, Materials Science, Production Engineering, Mining and Metallurgy, Traffic Engineering, Precision Mechanics
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/fld.1650181201
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  • 40
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    A preconditioned alternating inner-outer iterative solution method for the mixed finite element formulation of the Navier-Stokes equations (1994)
    Chichester : Wiley-Blackwell
    International Journal for Numerical Methods in Fluids 18 (1994), S. 1135-1151 
    Details
    ISSN: 0271-2091
    Keywords: Navier-Stokes ; Mixed formulation ; Bi-CGSTAB ; Incomplete LU ; Inner iterations ; Engineering ; Engineering General
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Mechanical Engineering, Materials Science, Production Engineering, Mining and Metallurgy, Traffic Engineering, Precision Mechanics
    Notes: In the present work a new iterative method for solving the Navier-Stokes equations is designed. In a previous paper a coupled node fill-in preconditioner for iterative solution of the Navier-Stokes equations proved to increase the convergence rate considerably compared with traditional preconditioners. The further development of the present iterative method is based on the same storage scheme for the equation matrix as for the coupled node fill-in preconditioner. This storage scheme separates the velocity, the pressure and the coupling of pressure and velocity coefficients in the equation matrix. The separation storage scheme allows for an ILU factorization of both the velocity and pressure unknowns. With the inner-outer solution scheme the velocity unknowns are eliminated before the resulting equation system for the pressures is solved iteratively. After the pressure unknown has been found, the pressures are substituted into the original equation system and the velocities are also found iteratively. The behaviour of the inner-outer iterative solution algorithm is investigated in order to find optimal convergence criteria for the inner iterations and compared with the solution algorithm for the original equation system. The results show that the coupled node fill-in preconditioner of the original equation system is more efficient than the coupled node fill-in preconditioner of the reduced equation system. However, the solution technique of the reduced equation system revals properties which may be advantageous in future solution algorithms.
    Additional Material: 4 Ill.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/fld.1650181202
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  • 41
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    Conference diary (1994)
    Chichester : Wiley-Blackwell
    International Journal for Numerical Methods in Fluids 18 (1994), S. 1211-1212 
    Details
    ISSN: 0271-2091
    Keywords: Engineering ; Engineering General
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Mechanical Engineering, Materials Science, Production Engineering, Mining and Metallurgy, Traffic Engineering, Precision Mechanics
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/fld.1650181206
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  • 42
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    Announcements (1994)
    Chichester : Wiley-Blackwell
    International Journal for Numerical Methods in Fluids 18 (1994), S. 1213-1214 
    Details
    ISSN: 0271-2091
    Keywords: Engineering ; Engineering General
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Mechanical Engineering, Materials Science, Production Engineering, Mining and Metallurgy, Traffic Engineering, Precision Mechanics
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/fld.1650181207
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    Two-phase flow modelling in gas-stirred liquid vessels with SUPG-stabilized equal-order interpolations (1994)
    Chichester : Wiley-Blackwell
    International Journal for Numerical Methods in Fluids 19 (1994), S. 1-22 
    Details
    ISSN: 0271-2091
    Keywords: Ladle ; Two-phase flow ; Navier-Stokes ; SUPG ; Streamline diffusion ; Stabilized algorithm ; Engineering ; Engineering General
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Mechanical Engineering, Materials Science, Production Engineering, Mining and Metallurgy, Traffic Engineering, Precision Mechanics
    Notes: The modelling of liquid flow in gas-stirred vessels is described. A simple two-phase model accounts for the buoyancy effect of bubbles. Friction between liquid and gas is modelled with the hypothesis of independent bubbles. The resulting PDE system is discretized with an original version of the SUPG-FEM technique which stabilizes both the convection term and equal-order interpolations for velocity and pressure, which are known to be unstable for incompressible flows. The resulting steady state discrete system is solved via pseudotemporal explicit iteration with a local time step and a preconditioning to homogenize the temporal scales for liquid and gas.
    Additional Material: 16 Ill.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/fld.1650190103
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  • 44
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    Newton's method for solving heat transfer, fluid flow and interface shapes in a floating molten zone (1994)
    Chichester : Wiley-Blackwell
    International Journal for Numerical Methods in Fluids 19 (1994), S. 41-65 
    Details
    ISSN: 0271-2091
    Keywords: Newton's method ; Interface ; Floating zone ; Thermocapillary flow ; Engineering ; Engineering General
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Mechanical Engineering, Materials Science, Production Engineering, Mining and Metallurgy, Traffic Engineering, Precision Mechanics
    Notes: Newton's method is applied to the finite volume approximation for the steady state heat transfer, fluid flow and unknown interfaces in a floating molten zone. The streamfunction/vorticity and temperature formulation of the Navier-Stokes and energy equations and their associated boundary conditions are written in generalized curvilinear co-ordinates and conservative law form with the Boussinesq approximation. During Newton iteration the ILU(0) preconditioned GMRES matrix solver is applied for solving the linear system, where the sparse Jacobian matrix is estimated by finite differences. Nearly quadratic convergence of the method is observed. Sample calculations are reported for sodium nitrate, a high-Prandtl-number material (Pr = 9.12). Both natural convection and thermocapillary flow as well as an overall mass balance constraint in the molten zone are considered. The effects of convection and heat input on the flow patterns, zone position and interface shapes are illustrated. After the lens effect due to the molten zone is considered, the calculated flow patterns and interface shapes are compared with the observed ones and are found to be in good agreement.
    Additional Material: 16 Ill.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/fld.1650190105
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  • 45
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    Masthead (1994)
    Chichester : Wiley-Blackwell
    International Journal for Numerical Methods in Fluids 19 (1994) 
    Details
    ISSN: 0271-2091
    Keywords: Engineering ; Engineering General
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Mechanical Engineering, Materials Science, Production Engineering, Mining and Metallurgy, Traffic Engineering, Precision Mechanics
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/fld.1650190201
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  • 46
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    Control volume finite element solution of confined turbulent swirling flows (1994)
    Chichester : Wiley-Blackwell
    International Journal for Numerical Methods in Fluids 19 (1994), S. 135-152 
    Details
    ISSN: 0271-2091
    Keywords: Turbulent flow ; Swirling flow ; k-∊ model ; Control volume ; Engineering ; Engineering General
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Mechanical Engineering, Materials Science, Production Engineering, Mining and Metallurgy, Traffic Engineering, Precision Mechanics
    Notes: A control volume finite element method that uses a triangular grid has been applied for solving confined turbulent swirling flows. To treat the velocity-pressure coupling, the vorticity-streamfunction formulation has been used. For turbulence effects the k-∊ model has been adopted. Consistent with the use of wall functions in the near-wall regions, a boundary condition for the calculation of the vorticity at computational boundaries is proposed and used effectively. The discretized equations are obtained by making use of an exponential interpolation function. Its use has been beneficial in reducing numerical diffusion. Comparisons of the current predictions with available experimental and numerical data from the literature showed generally fair agreement.
    Additional Material: 17 Ill.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/fld.1650190204
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  • 47
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    Co-located equal-order control-volume finite element method for two-dimensional axisymmetric incompressible fluid flow (1994)
    Chichester : Wiley-Blackwell
    International Journal for Numerical Methods in Fluids 18 (1994), S. 1-26 
    Details
    ISSN: 0271-2091
    Keywords: Axisymmetric flow ; Laminar flow ; Control-volume finite element method ; Mass-weighted skew upwind interpolation ; Flow-oriented upwind interpolation ; Engineering ; Engineering General
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Mechanical Engineering, Materials Science, Production Engineering, Mining and Metallurgy, Traffic Engineering, Precision Mechanics
    Notes: The formulation of a control-volume-based finite element method (CVFEM) for axisymmetric, two-dimensional, incompressible fluid flow and heat transfer in irregular-shaped domains is presented. The calculation domain is discretized into torus-shaped elements and control volumes. In a longitudinal cross-sectional plane, these elements are three-node triangles, and the control volumes are polygons obtained by joining the centroids of the three-node triangles to the mid-points of the sides. Two different interpolation schemes are proposed for the scalar-dependent variables in the advection terms: a flow-oriented upwind function, and a mass-weighted upwind function that guarantees that the discretized advection terms contribute positively to the coefficients in the discretized equations. In the discretization of diffusion transport terms, the dependent variables are interpolated linearly. An iterative sequential variable adjustment algorithm is used to solve the discretized equations for the velocity components, pressure and other scalar-dependent variables of interest. The capabilities of the proposed CVFEM are demonstrated by its application to four different example problems. The numerical solutions are compared with the results of independent numerical and experimental investigations. These comparisons are quite encouraging.
    Additional Material: 12 Ill.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/fld.1650180102
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  • 48
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    Conference diary (1994)
    Chichester : Wiley-Blackwell
    International Journal for Numerical Methods in Fluids 18 (1994), S. 123-125 
    Details
    ISSN: 0271-2091
    Keywords: Engineering ; Engineering General
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Mechanical Engineering, Materials Science, Production Engineering, Mining and Metallurgy, Traffic Engineering, Precision Mechanics
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/fld.1650180107
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  • 49
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    Modelling the non-linear interaction of wind and tide: Its influence on current profiles (1994)
    Chichester : Wiley-Blackwell
    International Journal for Numerical Methods in Fluids 18 (1994), S. 163-188 
    Details
    ISSN: 0271-2091
    Keywords: Non-linear interaction ; Hydrodynamic ; Spectral ; Finite difference ; Tidal current ; Wind-driven current ; Engineering ; Engineering General
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Mechanical Engineering, Materials Science, Production Engineering, Mining and Metallurgy, Traffic Engineering, Precision Mechanics
    Notes: A single-point model in the vertical is used to examine the coupling between tidal currents and wind-driven flows in shallow near-coastal regions. Calculations using both a linear slip and a no-slip condition at the sea bed clearly show that coupling between tidal and wind-driven currents cannot occur in a linear model with a time-independent eddy viscosity. However with a physically more realistic time-varying viscosity related to the flow field, coupling does occur, the magnitude of this non-linear interaction depending upon the change in eddy viscosity over a tidal cycle and the intensity of shear in the vertical. A point model in the vertical with flow induced by an oscillatory pressure gradient and an additional constant wind stress is used to examine the influence of viscosity parametrization and water depth upon this coupling.The solution in the vertical is accomplished using both a functional approach and a finite difference method. Some conclusions as to the relative merits of these approaches, particularly the use of a transformed grid in the case of high-shear surface and bed boundary layers, are made in the paper.
    Additional Material: 14 Ill.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/fld.1650180203
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  • 50
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    A new general-purpose least-squares finite element model for steady incompressible low-viscosity laminar flow using isoparametric C1-continuous Hermite elements (1994)
    Chichester : Wiley-Blackwell
    International Journal for Numerical Methods in Fluids 18 (1994), S. 215-226 
    Details
    ISSN: 0271-2091
    Keywords: Galerkin method ; Hermite, Lagrange and simplex finite elements ; Mixed UVP ; Continuous and discrete penalty ; Least-squares method ; Low-viscosity laminar flow ; Engineering ; Engineering General
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Mechanical Engineering, Materials Science, Production Engineering, Mining and Metallurgy, Traffic Engineering, Precision Mechanics
    Notes: This paper deals with a critical evaluation of various finite element models for low-viscosity laminar incompressible flow in geometrically complex domains. These models use Galerkin weighted residuals UVP, continuous penalty, discrete penalty and least-squares procedures. The model evaluations are based on the use of appropriate tensor product Lagrange and simplex quadratic triangular elements and a newly developed isoparametric Hermite element. All of the described models produce very accurate results for horizontal flows. In vertical flow domains, however, two different cases can be recognized. Downward flows, i.e. when the gravitational force is in the direction of the flow, usually do not present any special problem. In contrast, laminar flow of low-viscosity Newtonian fluids where the gravitational force is acting in the direction opposite to the flow presents a difficult case. We show that only by using the least-squares method in conjunction with C1-continuous Hermite elements can this type of laminar flow be modelled accurately. The problem of smooth isoparametric mapping of C1 Hermite elements, which is necessary in dealing with geometrically complicated domains, is tackled by means of an auxiliary optimization procedure. We conclude that the least-squares method in combination with isoparmetric Hermite elements offers a new general-purpose modelling technique which can accurately simulate all types of low-viscosity incompressible laminar flow in complex domains.
    Additional Material: 5 Ill.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/fld.1650180205
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    Linear and non-linear iterative methods for the incompressible Navier-Stokes equations (1994)
    Chichester : Wiley-Blackwell
    International Journal for Numerical Methods in Fluids 18 (1994), S. 229-256 
    Details
    ISSN: 0271-2091
    Keywords: Navier-Stokes ; Non-linear iteration ; Preconditioned conjugate gradient ; Engineering ; Engineering General
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Mechanical Engineering, Materials Science, Production Engineering, Mining and Metallurgy, Traffic Engineering, Precision Mechanics
    Notes: In this study, the discretized finite volume form of the two-dimensional, incompressible Navier-Stokes equations is solved using both a frozen coefficient and a full Newton non-linear iteration. The optimal method is a combination of these two techniques. The linearized equations are solved using a conjugate-gradient-like method (CGSTAB). Various types of preconditioning are developed. Completely general sparse matrix methods are used. Investigations are carried out to determine the effect of finite volume cell anisotropy on the preconditioner. Numerical results are given for several test problems.
    Additional Material: 9 Ill.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/fld.1650180302
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    Masthead (1994)
    Chichester : Wiley-Blackwell
    International Journal for Numerical Methods in Fluids 19 (1994) 
    Details
    ISSN: 0271-2091
    Keywords: Engineering ; Engineering General
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Mechanical Engineering, Materials Science, Production Engineering, Mining and Metallurgy, Traffic Engineering, Precision Mechanics
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/fld.1650190801
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  • 53
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    Effective downstream boundary conditions for incompressible Navier-Stokes equations (1994)
    Chichester : Wiley-Blackwell
    International Journal for Numerical Methods in Fluids 19 (1994), S. 693-705 
    Details
    ISSN: 0271-2091
    Keywords: Boundary conditions ; Artificial boundary ; Internal flow ; Incompressible flows ; Engineering ; Engineering General
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Mechanical Engineering, Materials Science, Production Engineering, Mining and Metallurgy, Traffic Engineering, Precision Mechanics
    Notes: The aim of this paper is to give open boundary conditions for the incompressible Navier-Stokes equations. From a weak formulation in velocity-pressure variables, some natural boundary conditions involving the traction or pseudotraction and inertial terms are established. Numerical experiments on the flow behind a cylinder show the efficiency of these conditions, which convey properly the vortices downstream. Comparisons with other boundary conditions for the velocity and pressure are also performed.
    Additional Material: 8 Ill.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/fld.1650190805
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  • 54
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    Announcements (1994)
    Chichester : Wiley-Blackwell
    International Journal for Numerical Methods in Fluids 19 (1994), S. 737-738 
    Details
    ISSN: 0271-2091
    Keywords: Engineering ; Engineering General
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Mechanical Engineering, Materials Science, Production Engineering, Mining and Metallurgy, Traffic Engineering, Precision Mechanics
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/fld.1650190809
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    A second-order radiation boundary condition for the shallow water wave equations on two-dimensional unstructured finite element grids (1994)
    Chichester : Wiley-Blackwell
    International Journal for Numerical Methods in Fluids 18 (1994), S. 575-604 
    Details
    ISSN: 0271-2091
    Keywords: Radiation boundary conditions ; Open boundary conditions ; Shallow water wave equations ; Sommerfeld condition ; Klein-Gordon equation ; Engineering ; Engineering General
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Mechanical Engineering, Materials Science, Production Engineering, Mining and Metallurgy, Traffic Engineering, Precision Mechanics
    Notes: A second-order radiation boundary condition (RBC) is derived for 2D shallow water problems posed in ‘wave equation’ form and is implemented within the Galerkin finite element framework. The RBC is derived by matching the dispersion relation for the interior wave equation with an approximate solution to the exterior problem for outgoing waves. The matching is correct to second order, accounting for curvature of the wave front and the geometry. Implementation is achieved by using the RBC as an evolution equation for the normal gradient on the boundary, coupled through the natural boundary integral of the Galerkin interior problem. The formulation is easily implemented on non-straight, unstructured meshes of simple elements. Test cases show fidelity to solutions obtained on extended meshes and improvement relative to simpler first-order RBCs.
    Additional Material: 28 Ill.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/fld.1650180604
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  • 56
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    Implicit schemes for unsteady Euler equations on triangular meshes (1994)
    Chichester : Wiley-Blackwell
    International Journal for Numerical Methods in Fluids 18 (1994), S. 647-668 
    Details
    ISSN: 0271-2091
    Keywords: Euler equations ; Finite element method ; Implicit scheme ; Unsteady flow ; Transonic flow ; Engineering ; Engineering General
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Mechanical Engineering, Materials Science, Production Engineering, Mining and Metallurgy, Traffic Engineering, Precision Mechanics
    Notes: An implicit finite element method is presented for the solution of steady and unsteady inviscid compressible flows on triangular meshes under transonic conditions. The method involves a first-order time-stepping scheme with a finite element discretization that reduces to central differencing on a rectangular mesh. On a solid wall the slip condition is prescribed and the pressure is obtained from an approximation of the normal momentum equation. With this solver no artificial viscosity is added to ensure the success of the calculation. Numerical examples are given for steady and unsteady cases.
    Additional Material: 12 Ill.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/fld.1650180703
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    Instability of uniform flow (1994)
    Chichester : Wiley-Blackwell
    International Journal for Numerical Methods in Fluids 19 (1994), S. 687-692 
    Details
    ISSN: 0271-2091
    Keywords: Open boundary conditions ; Flow stability ; Engineering ; Engineering General
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Mechanical Engineering, Materials Science, Production Engineering, Mining and Metallurgy, Traffic Engineering, Precision Mechanics
    Notes: We consider uniform flow of a Newtonian fluid trasverse to a domain bounded by parallel planes. We investigate the possibility of introducing instabilities in this flow by the choice of inflow and outflow conditions. Some instabilities of this kind are found.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/fld.1650190804
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  • 58
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    TVD algorithms for the solution of the compressible Euler equations on unstructured meshes (1994)
    Chichester : Wiley-Blackwell
    International Journal for Numerical Methods in Fluids 19 (1994), S. 827-847 
    Details
    ISSN: 0271-2091
    Keywords: TVD ; Unstructured mesh algorithms ; Euler equations ; Hypersonic flows ; Engineering ; Engineering General
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Mechanical Engineering, Materials Science, Production Engineering, Mining and Metallurgy, Traffic Engineering, Precision Mechanics
    Notes: The Galerkin finite element method is used as the basis for the construction of schemes for the solution of the two-dimensional compressible Euler equations on unstructured triangular grids. The use of a side-based data structure readily allows for the construction of a local (structured) stencil and the incorporation of a high-resolution shock-capturing method formulated within the TVD concept. The essential features of the finite element side-based scheme and the ID TVD approach are described and their numerical implementation is discussed. The choice of limiters and the support for their computation are analysed and the solutions of some inviscid flows, obtained by advancing explicitly in time, are presented.
    Additional Material: 18 Ill.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/fld.1650190906
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    Prediction of turbulent wall shear flows directly from wall (1994)
    Chichester : Wiley-Blackwell
    International Journal for Numerical Methods in Fluids 19 (1994), S. 869-888 
    Details
    ISSN: 0271-2091
    Keywords: k-∊ model ; Two-layer model ; Low-Reynolds number model ; Wall function method ; Engineering ; Engineering General
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Mechanical Engineering, Materials Science, Production Engineering, Mining and Metallurgy, Traffic Engineering, Precision Mechanics
    Notes: The fully elliptic Reynolds-averaged Navier-Stokes equations have been used together with Lam and Bremhorst's low-Reynolds-number model, Chen and Patel's two-layer model and a two-point wall function method incorporated into the standard k-∊ model to predict channel flows and a backward-facig step flow. These flows enable the evaluation of the performance of different near-wall treatments in flows involving streamwise and normal pressure gradients, flows with separation and flows with non-equilibrium turbulence characteristics. Direct numerical simulation (DNS) of a channel flow with Re =3200 further provides the detailed budgets of each modelling term of the k and ∊-transport equations. Comparison of model results with DNS data to evaluate the performance of each modelling term is also made in the present study. It is concluded that the low-Reynolds-number model has wider applicability and performs better than the two-layer model and wall function approaches. Comparison with DNS data further shows that large discrepancies exist between the DNS budgets and the modelled production and destruction terms of the ∊ equation. However, for simple channel flow the discrepancies are similar in magnitude but opposite in sign, so they are cancelled by each other. This may explain why, even when employing such an inaccurately modelled ∊-equation, one can still predict satisfactorily some simple turbulent flows.
    Additional Material: 14 Ill.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/fld.1650191002
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    Announcements (1994)
    Chichester : Wiley-Blackwell
    International Journal for Numerical Methods in Fluids 19 (1994), S. 959-960 
    Details
    ISSN: 0271-2091
    Keywords: Engineering ; Engineering General
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Mechanical Engineering, Materials Science, Production Engineering, Mining and Metallurgy, Traffic Engineering, Precision Mechanics
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/fld.1650191007
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  • 61
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    Numerical predictions of the bifurcation of confined swirling flows (1994)
    Chichester : Wiley-Blackwell
    International Journal for Numerical Methods in Fluids 19 (1994), S. 961-979 
    Details
    ISSN: 0271-2091
    Keywords: Confined flow ; Swirling flow ; Turbulence model ; Engineering ; Engineering General
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Mechanical Engineering, Materials Science, Production Engineering, Mining and Metallurgy, Traffic Engineering, Precision Mechanics
    Notes: The bifurcation of confined swirling flows was numerically investigated by employing both the k-∊ and algebraic stress turbulence models. Depending upon the branch solution examined, dual flow patterns were predicted at certain swirl levels. In the lower-branch solution which is obtained by gradually increasing the swirl level from a low-swirl flow, the flow changes with increasing swirl number from the low-swirl flow pattern to a high-swirl flow pattern. In the upper-branch solution which is acquired by gradually decreasing the swirl level from a high-swirl flow, on the other hand, the flow can maintain itself in the high-swirl flow pattern at the swirl levels where it exhibits the low-swirl flow pattern in the lower branch. The bifurcation of confined swirling flows was predicted with either the k-∊ model or the algebraic stress model being employed. Both the k-∊ and algebraic stress models result in comparable and sufficiently good predictions for confined swirling flows if high-order numerical schemes are used. The reported poor performance of the k-∊ model was clarified to be mainly attributable to the occurrence of the bifurcation and the use of low-order numerical schemes.
    Additional Material: 12 Ill.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/fld.1650191102
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    Efficient higher-order backward characteristics schemes for transient advection (1994)
    Chichester : Wiley-Blackwell
    International Journal for Numerical Methods in Fluids 19 (1994), S. 997-1012 
    Details
    ISSN: 0271-2091
    Keywords: Advection ; Method of characteristics ; Finite difference ; Flux limiter ; Engineering ; Engineering General
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Mechanical Engineering, Materials Science, Production Engineering, Mining and Metallurgy, Traffic Engineering, Precision Mechanics
    Notes: The use of the highest-order ((N - 1)th-order) Lagrangian interpolation Polynomial for the approximation of the exact solution in the backward characteristics scheme with N nodes is inefficient owing to the excessive number of terms in the polynomial. New schemes based on a combination of lower-order polynomials to approximate the exact solution are developed, with the relative weighting of the polynomials determined by Fourier mode analysis. With the addition of a flux limiter and a modified discriminator, the resulting schemes are oscillation-free, highly accurate, efficient and more cost-effective as compared with those schemes using the highest-order Lagrangian polynomial.
    Additional Material: 6 Ill.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/fld.1650191104
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  • 63
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    A numerical method for accelerating the rate of convergence of the SIMPLE-like algorithm for flow through a thin filter (1994)
    Chichester : Wiley-Blackwell
    International Journal for Numerical Methods in Fluids 19 (1994), S. 889-903 
    Details
    ISSN: 0271-2091
    Keywords: SIMPLE-like algorithm ; Average pressure correction ; Paper filter ; Turbulent flow ; Sampler ; Engineering ; Engineering General
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Mechanical Engineering, Materials Science, Production Engineering, Mining and Metallurgy, Traffic Engineering, Precision Mechanics
    Notes: The control volume, finite difference method and the k-∊ tubulence model are employed in a numerical simulation of the turbulent fluid flow both outside and inside a blunt cylindrical sampler which houses a paper filter in its chamber. The presence of a paper filter, which has a very large resistance, results in a large pressure drop across the filter and this causes difficulties in making the SIMPLE or the SIMPLEC scheme converge. In order to improve the rate of convergence of the SIMPLE-like algorithm when the resistance of the filter is very large, an average pressure correction formula is proposed. Based on global mass conservation, a line average pressure correction for the paper filter is derived using a modified Darcy law for a porous medium. A combination of this formula and the SIMPLE-like algorithm can rapidly build up the pressure drop across the filter and hence dramatically improve the rate of convergence of the iterative scheme. Comparisons of the convergence histories and the numerical results for the fluid flow when using SIMPLE and SIMPLEC with the average pressure correction method show that the average pressure correction method for dealing with the paper filter significantly accelerates the rate of convergence of the iterative scheme.
    Additional Material: 12 Ill.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/fld.1650191003
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    Dynamic vorticity condition: Theoretical analysis and numerical implementation (1994)
    Chichester : Wiley-Blackwell
    International Journal for Numerical Methods in Fluids 19 (1994), S. 905-938 
    Details
    ISSN: 0271-2091
    Keywords: Dynamic vorticity condition ; Theoretical analysis ; Engineering ; Engineering General
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Mechanical Engineering, Materials Science, Production Engineering, Mining and Metallurgy, Traffic Engineering, Precision Mechanics
    Notes: The dynamic boundary conditions for vorticity, derived from the incompressible Navier-Stokes equations, are examined from both theoretical and computational points of view. It is found that these conditions can be either local (Neumann type) or global (Dirichlet type), both containing coupling with the boundary pressure, which is the main difficulty in applying vorticity-based methods. An integral formulation is presented to analyse the structure of vorticity and pressure solutions, especially the strength of the coupling. We find that for high-Reynolds-number flows the coupling is weak and, if necessary, can be effectively bypassed by simple iteration. In fact, even a fully decoupled approximation is well applicable for most Reynolds numbers of practical interest. The fractional step method turns out to be especially appropriate for implementing the decoupled approximation. Both integral and finite difference methods are tested for some simple cases with known exact solutions. In the integral approach smoothed heat kernels are used to increase the accuracy of numerical quadrature. For the more complicated problem of impulsively started flow over a circular cylinder at Re = 9500 the finite difference method is used. The results are compared against numerical solutions and fine experiments with good agreement. These numerical experiments confirm our thoeretical analysis and show the advantages of the dynamic condition in computing high-Reynolds-number flows.
    Additional Material: 14 Ill.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/fld.1650191004
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    Computation of confined coflow jets with three turbulence models (1994)
    Chichester : Wiley-Blackwell
    International Journal for Numerical Methods in Fluids 19 (1994), S. 939-956 
    Details
    ISSN: 0271-2091
    Keywords: Turbulence models ; Confined jets ; Recirculation ; Engineering ; Engineering General
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Mechanical Engineering, Materials Science, Production Engineering, Mining and Metallurgy, Traffic Engineering, Precision Mechanics
    Notes: A numerical study of confined jets in a cylindrical duct is carried out to examine the performance of two recently proposed turbulence models: an RNG-based K-∊ model and a realizable Reynolds stress algebraic equation model. The former is of the same form as the standard K-∊ model but has different model coefficients. The latter uses an explicit quadratic stress-strain relationship to model the turbulent stresses and is capable of ensuring the positivity of each turbulent normal stress. The flow considered involves recirculation with unfixed separation and reatachment points and severe adverse pressure gradients, thereby providing a valuable test of the predictive capability of the models for complex flows. Calculations are performed with a finite volume procedure. Numerical credibility of the solutions is ensured by using second-order-accurate differencing schemes and sufficiently fine grids. Calculations with the standard K-∊ model are also made for comparison. Detailed comparisons with experiments show that the realizable Reynolds stress algebraic equation model consistently works better than does the standard K-∊ model in capturing the essential flow features, while the RNG-based K-∊ model does not seem to give improvements over the standard K-∊ model under the flow conditions considered.
    Additional Material: 12 Ill.
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    URL: http://dx.doi.org/10.1002/fld.1650191005
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    Masthead (1994)
    Chichester : Wiley-Blackwell
    International Journal for Numerical Methods in Fluids 19 (1994) 
    Details
    ISSN: 0271-2091
    Keywords: Engineering ; Engineering General
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Mechanical Engineering, Materials Science, Production Engineering, Mining and Metallurgy, Traffic Engineering, Precision Mechanics
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/fld.1650191101
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    Pressure-based method for combustion instability analysis (1994)
    Chichester : Wiley-Blackwell
    International Journal for Numerical Methods in Fluids 19 (1994), S. 981-995 
    Details
    ISSN: 0271-2091
    Keywords: Pressure-based method ; All-speed ; Blast wave ; Two-phase flow ; Combustion instability ; Engineering ; Engineering General
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Mechanical Engineering, Materials Science, Production Engineering, Mining and Metallurgy, Traffic Engineering, Precision Mechanics
    Notes: An improved pressure-based method has been applied to predict the two-dimensional instability analysis of liquid-fuelled rocket engines. This method is non-iterative for transient flow calculations and applicable to all-speed flows. Validation cases include the shock-tube problem, the blast flow field and unsteady spraycombusting flows. Computations for the combustion instability analysis were carried out for various combustion parameters such as spray initial conditions and combustor geometries. Unsteady behaviours of the stable and unstable spray flame fields and effects of acoustic oscillations on the fuel droplet vaporization and combustion process are studied in detail. The present numerical model successfully demonstrates the capability of predicting combustion instability as well as fast transient compressible flows at all speeds.
    Additional Material: 14 Ill.
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    URL: http://dx.doi.org/10.1002/fld.1650191103
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    Announcements (1994)
    Chichester : Wiley-Blackwell
    International Journal for Numerical Methods in Fluids 19 (1994), S. 1051-1053 
    Details
    ISSN: 0271-2091
    Keywords: Engineering ; Engineering General
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Mechanical Engineering, Materials Science, Production Engineering, Mining and Metallurgy, Traffic Engineering, Precision Mechanics
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/fld.1650191108
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    Editorial (1994)
    Chichester : Wiley-Blackwell
    International Journal for Numerical Methods in Fluids 19 (1994), S. i 
    Details
    ISSN: 0271-2091
    Keywords: Engineering ; Engineering General
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Mechanical Engineering, Materials Science, Production Engineering, Mining and Metallurgy, Traffic Engineering, Precision Mechanics
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/fld.1650191109
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  • 70
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    Three-dimensional modelling of steam flush for DNAPL site remediation (1994)
    Chichester : Wiley-Blackwell
    International Journal for Numerical Methods in Fluids 19 (1994), S. 1055-1081 
    Details
    ISSN: 0271-2091
    Keywords: Multiphase porous media flow ; Primary variable selection ; Horizontal wells ; Engineering ; Engineering General
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Mechanical Engineering, Materials Science, Production Engineering, Mining and Metallurgy, Traffic Engineering, Precision Mechanics
    Notes: Numerical simulation of steam flush for clean-up of non-aqueous phase liquid (NAPL) contaminated groundwater sites involves solution of the multiphase, multicomponent subsurface flow equations. This paper describes techniques for discretizing problems with horizontal wells in a three-dimensiontetrahedral mesh. The effectiveness of non-linear flux limiters for reducing numerical dispersion is discussed. Primary variable selection and thermodynamic state transition rules will also be compared. Some example results for several steam flush scenarios will be presented.
    Additional Material: 21 Ill.
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    URL: http://dx.doi.org/10.1002/fld.1650191202
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    Conference diary (1994)
    Chichester : Wiley-Blackwell
    International Journal for Numerical Methods in Fluids 19 (1994), S. 1137-1138 
    Details
    ISSN: 0271-2091
    Keywords: Engineering ; Engineering General
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Mechanical Engineering, Materials Science, Production Engineering, Mining and Metallurgy, Traffic Engineering, Precision Mechanics
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/fld.1650191206
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    Numerical modelling and computation of fluid pressure transients with air entrainment in pumping installations (1994)
    Chichester : Wiley-Blackwell
    International Journal for Numerical Methods in Fluids 19 (1994), S. 89-103 
    Details
    ISSN: 0271-2091
    Keywords: Air entrainment ; Pressure surges ; Wave speed ; Pumping installations ; Engineering ; Engineering General
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Mechanical Engineering, Materials Science, Production Engineering, Mining and Metallurgy, Traffic Engineering, Precision Mechanics
    Notes: In pumping installations such as sewage pumping stations, where gas content and air entrainment exist, the computation of fluid pressure transients in pipelines becomes grossly inaccurate when a constant wave speed is assumed. An accurate numerical model with gas release and absorption has been developed in this paper and used to compute the fluid pressure transients in the pumping mains of selected pumping installations. Free and dissolved gases in the transported fluid and cavitation at vapour pressure are also modelled. When compared with the gas-free case, computations show that entrained, entrapped or released gases amplify the positive pressure peak, increase surge damping and produce asymmetric pressure surges. While the upsurge with air entrainment in the pipelines was considerably amplified, the downsurge was only marginally reduced. The computed results show good agreement with the data available.
    Additional Material: 12 Ill.
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    URL: http://dx.doi.org/10.1002/fld.1650190202
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    Conference diary (1994)
    Chichester : Wiley-Blackwell
    International Journal for Numerical Methods in Fluids 19 (1994), S. 363-364 
    Details
    ISSN: 0271-2091
    Keywords: Engineering ; Engineering General
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Mechanical Engineering, Materials Science, Production Engineering, Mining and Metallurgy, Traffic Engineering, Precision Mechanics
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/fld.1650190406
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  • 74
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    Computation of free surface waves around an arbitrary body by a Navier-Stokes solver using the psuedocompressibility technique (1994)
    Chichester : Wiley-Blackwell
    International Journal for Numerical Methods in Fluids 19 (1994), S. 395-413 
    Details
    ISSN: 0271-2091
    Keywords: Euler implicit scheme ; Pseudocompressibility ; Moving grid system ; Free surface fitting ; Baldwin-Lomax turbulence model ; Engineering ; Engineering General
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Mechanical Engineering, Materials Science, Production Engineering, Mining and Metallurgy, Traffic Engineering, Precision Mechanics
    Notes: A Navier-Stokes equation solver is developed for computing free surface wave and viscous flow around an arbitrary body, in which a free surface model is introduced into the pseudocompressibility solution. The governing equations are classified in a vectorial form, with primitive variables, and a block diagonal system is generated by the discretization of an implicit factorization method. A moving grid system fitted to both the free surface and body surface is generated by an effective cubic spline fitting technique. Two zero-equation turbulence models, namely the Cebeci-Smith model and the Baldwin-Lomax model, are used for turbulent calculations. Numerical simulations are carried out for the free surface viscous flows generated by a submerged hydrofoil and a ship model. Computed results are in reasonable agreement with measurements.
    Additional Material: 14 Ill.
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    URL: http://dx.doi.org/10.1002/fld.1650190504
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    Announcements (1994)
    Chichester : Wiley-Blackwell
    International Journal for Numerical Methods in Fluids 19 (1994), S. 459-462 
    Details
    ISSN: 0271-2091
    Keywords: Engineering ; Engineering General
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Mechanical Engineering, Materials Science, Production Engineering, Mining and Metallurgy, Traffic Engineering, Precision Mechanics
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/fld.1650190508
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    Fully coupled finite volume solutions of the incompressible Navier-Stokes and energy equations using an inexact Newton method (1994)
    Chichester : Wiley-Blackwell
    International Journal for Numerical Methods in Fluids 19 (1994), S. 439-455 
    Details
    ISSN: 0271-2091
    Keywords: Incompressible Navier-Stokes ; Newton's method ; Conjugate gradient ; Engineering ; Engineering General
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Mechanical Engineering, Materials Science, Production Engineering, Mining and Metallurgy, Traffic Engineering, Precision Mechanics
    Notes: An inexact Newton method is used to solve the steady, incompressible Navier-Stokes and energy equation. Finite volume differencing is employed on a staggered grid using the power law scheme of Patankar. Natural convection in an enclosed cavity is studied as the model problem. Two conjugate-gradient -like algorithms based upon the Lanczos biorthogonalization procedure are used to solve the linear systems arising on each Newton iteration. The first conjugate-gradient-like algorithm is the transpose-free quasi-minimal residual algorithm (TFQMR) and the second is the conjugate gradients squared algorithm (CGS). Incomplete lower-upper (ILU) factorization of the Jacobian matrix is used as a right preconditioner. The performance of the Newton- TFQMR algorithm is studied with regard to different choices for the TFQMR convergence criteria and the amount of fill-in allowed in the ILU factorization. Performance data are compared with results using the Newton-CGS algorithm and previous results using LINPACK banded Gaussian elimination (direct-Newton). The inexact Newton algorithms were found to be CPU competetive with the direct-Newton algorithm for the model problem considered. Among the inexact Newton algorithms, Newton-CGS outperformed Newton- TFQMR with regard to CPU time but was less robust because of the sometimes erratic CGS convergence behaviour.
    Additional Material: 4 Ill.
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    URL: http://dx.doi.org/10.1002/fld.1650190506
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    Masthead (1994)
    Chichester : Wiley-Blackwell
    International Journal for Numerical Methods in Fluids 19 (1994) 
    Details
    ISSN: 0271-2091
    Keywords: Engineering ; Engineering General
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Mechanical Engineering, Materials Science, Production Engineering, Mining and Metallurgy, Traffic Engineering, Precision Mechanics
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/fld.1650191201
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  • 78
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    Embryonic expression of the single Tribolium engrailed homolog (1994)
    Chichester [u.a.] : Wiley-Blackwell
    Developmental Genetics 15 (1994), S. 7-18 
    Details
    ISSN: 0192-253X
    Keywords: Tribolium ; engrailed ; embryogenesis ; segmentation ; Life and Medical Sciences ; Genetics
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Biology
    Notes: We have cloned and sequenced the single Tribolium homolog of the Drosophila engrailed gene. The predicted protein contains a homeobox and several domains conserved among all engrailed genes identified to date. In addition it contains several features specific to the invected homologs of Bombyx and Drosophila, indicating that these features most likely were present in the ancestral gene in the common ancestor of holometabolous insects. We used the cross-reacting monoclonal antibody, 4D9, to follow the expression of the Engrailed protein during segmentation in Tribolium embryos. As in other insects, Engrailed accumulates in the nuclei of cells along the posterior margin of each segment. The first Engrailed stripe appears as the embryonic rudiment condenses. Then as the rudiment elongates into a germ band, Engrailed stripes appear in an anterior to posterior progression, just prior to morphological evidence of the formation of each segment. As in Drosophila (a long germ insect), expression of engrailed in Tribolium (classified as a short germ insect) is preceeded by the expression of several homologous segmentation genes, suggesting that similar genetic regulatory mechanisms are shared by diverse developmental types. © 1994 Wiley-Liss, Inc.
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    URL: http://dx.doi.org/10.1002/dvg.1020150103
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    Developmental evolution: New paradigms and paradoxes (1994)
    Chichester [u.a.] : Wiley-Blackwell
    Developmental Genetics 15 (1994), S. 1-6 
    Details
    ISSN: 0192-253X
    Keywords: Evolution ; homeobox gene ; body plan ; comparative method ; Life and Medical Sciences ; Genetics
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Biology
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/dvg.1020150102
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  • 80
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    Homeotic gene expression in the locust Schistocerca: An antibody that detects conserved epitopes in ultrabithorax and abdominal-A proteins (1994)
    Chichester [u.a.] : Wiley-Blackwell
    Developmental Genetics 15 (1994), S. 19-31 
    Details
    ISSN: 0192-253X
    Keywords: Homeobox ; Ultrabithorax ; abdominal-A ; short germ development ; grasshopper ; evolution ; Life and Medical Sciences ; Genetics
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Biology
    Notes: To investigate what role homeotic genes may play in morphological evolution, we are comparing homeotic gene expression in two very different insects, Drosophila (Diptera) and Schistocerca (Orthoptera). In this paper we describe a monoclonal antibody, FP6.87, that recognizes the products of both the Ultrabithorax (Ubx) and abdominal-A (abd-A) genes in Drosophila, via an epitope common to the carboxy terminal region of these two proteins. This antibody recognizes nuclear antigens present in the posterior thorax and abdomen of Schistocerca. We infer that it recognizes the Schistocerca homolog of UBX protein, and probably also of ABD-A. As the distribution of Schistocerca ABD-A protein is already known, we can use this reagent to map the expression of Schistocerca UBX in the thorax and anterior abdomen, where ABD-A is not expressed. Both the general domain, and many of the details, of UBX exp ression are remarkably conserved compared with Drosophila. Thus UBX expression extends back from T2 in the ectoderm (including the CNS), but only from A1 in the mesoderm. As noted for other bithorax complex genes in Schistocerca, expression begins in the abdomen, at or shortly before the time of segmentation. It only later spreads anteriorly to the thorax. For much of embryogene-sis, the expression of UBX in the thoracic epidermis is largely restricted to the T3 limb. Inthis limb, UBX is strikingly regulated, in a complex pattern that reflects limb segmentation.Reviewing these and earlier observations, we conclude that evolutionary changes affect both the precise regulation of homeotic genes within segments, and probably also the spectrum of downstream genes that respond to homeotic gene expression in a given tissue. Overall domains of homeotic gene expression appear to be well conserved between different insect groups, though a change in the extent and timing of homeotic gene expression may underlie the modification of the posterior abdomen in different insect groups. © 1994 Wiley-Liss, Inc.
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    URL: http://dx.doi.org/10.1002/dvg.1020150104
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    Characterization and expression of C/EBP-like genes in the liver of Rana catesbeiana tadpoles during spontaneous and thyroid hormone-induced metamorphosis (1994)
    Chichester [u.a.] : Wiley-Blackwell
    Developmental Genetics 15 (1994), S. 366-377 
    Details
    ISSN: 0192-253X
    Keywords: C/EBP ; thyroid hormone ; metamorphosis ; gene expression ; Rana cafesbeiana ; bZlP proteins ; Life and Medical Sciences ; Genetics
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Biology
    Notes: Tissue-specific changes in gene expression occur in the liver of Rana cafesbeiana tadpoles undergoing metamorphosis. Many of these changes can be induced precociously by administration of thyroid hormone (TH) to a tadpole or to cultured tadpole liver. While the precise molecular means by which TH exerts a tissue-specific response is unknown, recent studies suggest that the expression of genes which are liver-specific and characteristic of the adult liver phenotype may rely on TH-induction of tissue-specific transcription factors, as well as the thyroid hormone receptor proteins. Guided by this notion, we screened our Rana catesbeiana liver cDNA library and isolated clones, RcC/EBP-1 and -2, encoding Rana homologues of a mammalian transcription factor, C/EBP (CCAAT/enhancer core binding protein), implicated in the expression of liver-specific genes and terminal differentiation of hepatocytes. Gel mobility shift assays demonstrate that the proteins synthesized from these cDNAs bind specifically to the consensus binding site for C/EBP-related proteins. Characterization of the amino acid sequence in the bZlP DNA-binding domains of these proteins suggests that RcC/EBP-1 and -2 encode Rana homologues of C/EBPα and δ, respectively. Hybridization analyses demonstrate that the amount of RcC/EBP-2 mRNAs in tadpole liver remains constant throughout metamorphosis, whereas RcC/EBP-1 mRNAs are up-regulated during both spontaneous and TH-induced metamorphosis. The TH-induced up-regulation of RcC/ EBP-1 mRNAs precedes the up-regulation of liver-specific urea cycle enzyme mRNAs by 6 to 12 hours. These results, coupled with in situ hybridization studies, suggest that RcC/EBP-1 mRNAs encode a transcription factor which may play an early role(s) in the terminal differentiation and/or reprogramming of gene expression in this tadpole's liver cells during both spontaneous and TH-induced metamorphosis. ©1994 WiIey-Liss, Inc.
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    Interactions between tassel seed genes and other sex determining genes in maize (1994)
    Chichester [u.a.] : Wiley-Blackwell
    Developmental Genetics 15 (1994), S. 155-171 
    Details
    ISSN: 0192-253X
    Keywords: Sex determination ; epistasis ; floral development ; Life and Medical Sciences ; Genetics
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Biology
    Notes: The tassel seed mutations of maize cause sex reversal of the florets of the tassel, such that the normally staminate florets develop pistils. Although these mutations have been recognized for many years, little is known about how they act. We have tested the hypothesis that the tassel seed genes interact directly with each other and with other genes controlling sex determination in a single genetic pathway by the construction and analysis of double mutants. On the basis of the phenotypes of the double mutants, the tassel seed mutations were placed into two groups: ts1, ts2, Ts5 and ts4, Ts6. Both groups of tassel seed mutations were additive with the masculinizing mutation dwarf, indicating independent modes of action. Interactions of tassel seed mutations with silkless varied, allowing the ordering of the action of the various tassel seed mutations relative to silkless. Both groups of tassel seed mutations were epistatic with regard to sex expression to mutations that alter both architecture of the plant and distribution of male and female florets, Teopod 1, terminal ear, and teosinte branched. Thus, there are at least two separate genetic pathways that control the sex of florets in maize tassels. In addition, analysis of double mutants revealec that all tassel seed genes tested play a role in the regulation of flower morphogenesis as well as pistil suppression. © 1994 Wiley-Liss, Inc.
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    URL: http://dx.doi.org/10.1002/dvg.1020150206
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    Sex determination and differentiation (1994)
    Chichester [u.a.] : Wiley-Blackwell
    Developmental Genetics 15 (1994), S. 201-204 
    Details
    ISSN: 0192-253X
    Keywords: Life and Medical Sciences ; Genetics
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Biology
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/dvg.1020150302
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    Genetics of sex determination in flowering plants (1994)
    Chichester [u.a.] : Wiley-Blackwell
    Developmental Genetics 15 (1994), S. 214-230 
    Details
    ISSN: 0192-253X
    Keywords: Sex determination ; angiosperms ; genetics ; white campion ; sex chromosomes ; Life and Medical Sciences ; Genetics
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Biology
    Notes: Most flowering plant species are hermaphroditic, but a small number of species in most plant families are unisexual (i.e., an individ-ual will produce only male or female gametes). Because species with unisexual flowers have evolved repeatedly from hermaphroditic progenitors, the mechanisms controlling sex determination in flowering plants are extremely diverse. Sex is most strongly determined by genotype in all species but the mechanisms range from a single controlling locus to sex chromosomes bearing several linked locirequired for sex determination. Plant hormones also influence sex expression with variable effects from species to species. Here, we review the genetic control of sex determination from a number of plant species to illustrate the variety of extant mechanisms. We emphasize species that are now used as models to investigate the molecular biology of sex determination. We also present our own investigations of the structure of plant sex chromosomes of white campion (Silene latifolia - Melan-drium album). The cytogenetic basis of sex determination in white campion is similar to mammals in that it has a male-specific Y-chromosome that carries dominant male determining genes. If one copy of this chromosome is in the genome, the plant is male. Otherwise it is female. Like mammalian Y-chromosomes, the white campion Y-chromosome is rich in repetitive DNA. We isolated repetitive sequences from microdissected Y-chromosomes of white campion to study the distribution of homologous repeated sequences on the Y-chromosome and the other chromosomes. We found the Y to be especially rich in repetitive sequences that were generally dispersed over all the white campion chromosomes. Despite its repetitive character, the Y-chromosome is mainly euchromatic. This may be due to the relatively recent evolution of the white campion sex chromosomes compared to the sex chromosomes of animals. © 1994 Wiley-Liss, Inc.
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    URL: http://dx.doi.org/10.1002/dvg.1020150304
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    Masthead (1994)
    Chichester [u.a.] : Wiley-Blackwell
    Developmental Genetics 15 (1994) 
    Details
    ISSN: 0192-253X
    Keywords: Life and Medical Sciences ; Genetics
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Biology
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/dvg.1020150401
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    Tissue-specific regulation by ecdysone: Distinct patterns of Eip28/29 expression are controlled by different ecdysone response elements (1994)
    Chichester [u.a.] : Wiley-Blackwell
    Developmental Genetics 15 (1994), S. 320-331 
    Details
    ISSN: 0192-253X
    Keywords: Drosophila melanogaster ; ecdysone ; steroid ; Eip28/29 ; EcREs ; lacZ ; Life and Medical Sciences ; Genetics
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Biology
    Notes: The Eip28/29 gene of Drosophila is an example of a tissue- and stage-specific ecdysone-responsive gene. Its diverse patterns of expression during the third larval instar and a synopsis of those patterns in terms of expression groups have been reported previously. Here we have studied the expression (in transgenic flies) of reporter genes controlled by Eip28/29-derived flanking DNA. During the middle and late third instar, most tissues exhibit normal expression patterns when controlled by one of two classes of regulatory sequences. Class A sequences include only 657 Np of 5′ flanking DNA from Eip28/29. Class B sequences include an extended 3′ flanking region and a minimal (≤93 Np) 5′ flanking region. The class B sequences include all those elements known to be important for ecdvsone induction in cultured cells. They are sufficient to direct the normal premetamorphic induction of Eip28/29 in the lymph glands, hemocytes, proventriculus, and Malpighian tubules. This is consistent with our suggestion that Kc cells are derived from embryonic hematopoietic cells. It is remarkable that the epidermis requires only class A sequences. These are sufficient to up-regulate expression at medinstar and to down-regulate expression at metamorphosis. It follows that the epidermis uses EcREs distinct from those that function in Kc cells. It is possible that the Upstream EcRE, which is nearly silent in Kc cells, is active in the epidermis. © 1994 Wiley-Liss, Inc.
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    URL: http://dx.doi.org/10.1002/dvg.1020150403
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    Upregulation of AP-2 in the skin of Xenopus laevis during thyroid hormone-induced metamorphosis (1994)
    Chichester [u.a.] : Wiley-Blackwell
    Developmental Genetics 15 (1994), S. 356-365 
    Details
    ISSN: 0192-253X
    Keywords: Thyroid hormone ; AP-2 ; Xenopus luevis ; metamorphosis ; 63 kDa keratin gene ; epidermal differentiation ; Life and Medical Sciences ; Genetics
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Biology
    Notes: During amphibian metamorphosis dramatic changes occur in the morphogenesis and differentiation of the epidermis. Concurrently with these changes, the 63 kDa keratin geneis upregulated from low basal levels to high levels. What makes these processes unique is that they are controlled by triiodothyronine (T3) and can be duplicated in cultures of purified epidermal cells. Since there is a 2 day lag period between the addition of T3 and the upregulation of keratin gene expression and terminal differentiation, recent studies have focused on identifying the genes activated during the lag period. We assume that the transcription factors required for upregulation of the keratin gene are induced by T3 during the lag period, and therefore we have cloned the keratin gene so that promoter analyses can be conducted. S1 mapping assays have shown that the same transcription start sites are used during premetamorphosis when the keratin gene is basally expressed, during metamorphosis when it is T3-upregulated, and in the adult epidermis where it is expressed independently of T3. During the early part of the lag period TRP and AP-2 mRNA levels are upregulated in the epidermis by T3. The transcription factor AP-2 is expressed at high levels in the skin of premetamorphic larvae and induced about fivefold by T3 but is not induced in an epithelial cell line (XL-177). Since the keratin mRNA, AP-2 rnRNA, and other genes induced during the lag period are expressed in premetamorphic larvae it appears that T3 functions by upregulating the expression of genes previously activated by a T3-independent process. This preprogramming may account for the tissue specificity of T3 action during metamorphosis. © 1994 WiIey. Liss, Inc.
    Additional Material: 5 Ill.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/dvg.1020150407
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  • 88
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    Masthead (1994)
    Chichester [u.a.] : Wiley-Blackwell
    Developmental Genetics 15 (1994) 
    Details
    ISSN: 0192-253X
    Keywords: Life and Medical Sciences ; Genetics
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Biology
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/dvg.1020150501
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  • 89
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    Developmental arrest of fertilized eggs from the B6.YDOM sex-reversed female mouse (1994)
    Chichester [u.a.] : Wiley-Blackwell
    Developmental Genetics 15 (1994), S. 435-442 
    Details
    ISSN: 0192-253X
    Keywords: Fertility ; sex-reversal ; XY ovary ; XY oocyte ; mouse ; Life and Medical Sciences ; Genetics
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Biology
    Notes: When the Y chromosome of a Mus musculus domesticus mouse strain is placed onto the C57BL/6J (B6) inbred background, the XY progeny develop ovaries or ovotestes but never normal testes during fetal life. While some of the hermaphroditic males become fertile, none of the XY females produces litters. Here, we examined the fertility and development of oocytes derived from the XY female mouse. With or without preceding injection of gonadotropins, female mice were mated with normal B6 males, and their embryos were recovered at various developmental stages. In vitro fertilization was performed with the eggs recovered from the oviduct after treatment with go-nadotropins. Development of embryos was examined by both light and electron microscopy. The results indicate that the oocytes released from the B6.YDOM ovary were efficiently fertilized and often initiated the first cell cleavage, but all embryos died during early preimplantation periods. Even when oocytes were fertilized in vitro, minimizing their exposure to the XY oviduct/uterus environment, most embryos died at the 1- or 2-cell stage. A few exceptional embryos reached the 4- or 8-cell stage, but abnormalities were evident in both nuclear and cytoplasmic structures of all embryos. After cleavage, neighbouring blastomeres were only loosely associated, and microvilli were abundant at the intercellular interfaces. We postulate that oocytes of the B.6.YDOM female mouse become defective during XY ovarian differentiation, and, hence, fail to proceed through normal embryonic development. © 1994 Wiley-Liss, Inc.
    Additional Material: 3 Ill.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/dvg.1020150506
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  • 90
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    Heterochronic expression of an adult muscle actin gene during ascidian larval development (1994)
    Chichester [u.a.] : Wiley-Blackwell
    Developmental Genetics 15 (1994), S. 51-63 
    Details
    ISSN: 0192-253X
    Keywords: Actin ; ascidian development ; gene expression ; heterochrony ; muscle actin gene ; Life and Medical Sciences ; Genetics
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Biology
    Notes: Adultation is a hetercchronic mode of development in which adult tissues and organs differentiate precociously during the larval phase. We have investigated the expression of an adult muscle actin gene during adultation in the ascidian Molgula citrina. Ascidians contain multiple muscle actin genes which are expressed in the larva, the adult, or during both phases of the life cycle. In ascidian species with conventional larval development, the larval mesenchyme cells, which are believed to be progenitors of the adult mesoderm, remain undifferentiated and do not express the muscle actin genes. In M. citrina, the mesen-chyme cells differentiate precociously during larval development, suggesting a role in adultation. An adult muscle actin gene from M. citrina was obtained by screening a mantle cDNA library with a probe containing the coding region of SpMAl, a Styela plicata adult muscle actin gene. The screen yielded a cDNA clone designated McMAl, which contained virtually the complete coding and 3′ noncoding regions of a muscle actin gene. The deduced McMAl and SpMAl proteins exhibit 97% identity in amino acid sequence and may be encoded by homologous genes. The McMAl gene is expressed in juveniles and adults, but not in larval tail muscle cells, suggesting that it is an adult muscle actin gene. In situ hybridization with a 3′ non-coding region probe was used to determine whether the McMAl gene is expressed during adultation in M. citrina. McMAl mRNA was first detected exclusively in the mesenchyme cells during the late tailbud stage and continued to accumulate in these cells during their migration into the future body cavity and heart primordium in the hatched larva. The McMAl transcripts persisted in mesenchyme cells after larval metamorphosis. It is concluded that an adult muscle actin gene shows a heterochronic shift of expression into the larval phase during adultation in M. citrina.
    Additional Material: 9 Ill.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/dvg.1020150107
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  • 91
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    Masthead (1994)
    Chichester [u.a.] : Wiley-Blackwell
    Developmental Genetics 15 (1994) 
    Details
    ISSN: 0192-253X
    Keywords: Life and Medical Sciences ; Genetics
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Biology
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/dvg.1020150201
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  • 92
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    Action of the Tunicate locus on maize floral development (1994)
    Chichester [u.a.] : Wiley-Blackwell
    Developmental Genetics 15 (1994), S. 176-187 
    Details
    ISSN: 0192-253X
    Keywords: Floral development ; floral genetics ; Tunicate maize ; Life and Medical Sciences ; Genetics
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Biology
    Notes: The co-dominant Tunicate (Tu) mutation in maize causes nonreproductive structures in both the male and female inflorescences to be enlarged. This mutation also affects sex determination, permitting the development of pistils in the normally staminate tassel. In order to characterize the role of the normal tu gene product, we have analysed genetic interaction between Tu and other mutations that perturb specific stages of floral development. Synergistic interactions observed suggested that the tu product functions in at least three stages of floral development-determination of spikelet primordia, differentiation of non-reproductive organs and pistil abortion in the tassel. © 1994 Wiley-Liss, Inc.
    Additional Material: 8 Ill.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/dvg.1020150208
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  • 93
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    Advantages of sexual reproduction (1994)
    Chichester [u.a.] : Wiley-Blackwell
    Developmental Genetics 15 (1994), S. 205-213 
    Details
    ISSN: 0192-253X
    Keywords: Sex ; sexual reproduction ; recombination ; diploidy ; anisogamy ; Life and Medical Sciences ; Genetics
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Biology
    Notes: Despite the obvious efficiencies of many forms of asexual reproduction, sexual reproduction abounds. Asexual species, for the most part, are relatively short-lived offshoots of sexual ancestors. From the nineteenth century, it has been recognized that, since there is no obvious advantage to the individuals involved, the advantages of sexual reproduction must be evolutionary. Furthermore, the advantage must be substantial; for example, producing males entails a two-fold cost, compared to dispensing with them and reproducing by parthenogenetic females.There are a large number of plausible hypotheses. To me the most convincing of these are two. The first hypothesis, and the oldest, is that sexual reproduction offers the opportunity to produce recombinant types that can make the population better able to keep up with changes in the environment. Although the subject of a great deal of work, and despite its great plausibility, the hypothesis has been very difficult to test by critical observations or experiments.Second, species with recombination can bunch harmful mutations together and eliminate several in a single “genetic death.” Asexual species, can eliminate them only in the same genotype in which they occurred. If the rate of occurrence of deleterious mutations is one or more per zygote, some mechanism for eliminating them efficiently must exist. A test of this mutation load hypothesis for sexual reproduction, then, is to find whether deleterious mutation rates in general are this high-as Drosophila data argue. Unfortunately, although molecular and evolutionary studies can give information on the total mutation rate, they cannot determine what fraction are deleterious.In addition, there are short discussions of the advantages of diploidy, anisogamy, and separate sexes. © 1994 Wiley-Liss, Inc.
    Additional Material: 1 Ill.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/dvg.1020150303
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  • 94
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    Temperature-dependent sex determination in reptiles: Proximate mechanisms, ultimate outcomes, and practical applications (1994)
    Chichester [u.a.] : Wiley-Blackwell
    Developmental Genetics 15 (1994), S. 297-312 
    Details
    ISSN: 0192-253X
    Keywords: Sex determination ; sexual differentiation ; reptiles ; temperature-dependent sex determination ; behavior ; steroidogenic enzymes ; aromatase ; reductase ; estrogen ; androgen ; steroid hormone receptors ; Life and Medical Sciences ; Genetics
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Biology
    Notes: In many egg-laying reptiles, the incubation temperature of the egg determines the sex of the offspring, a process known as temperature-dependent sex determination (TSD). In TSD sex determination is an “all or none” process and intersexes are rarely formed. How is the external signal of temperature transduced into a genetic signal that determines gonadal sex and channels sexual development? Studies with the red-eared slider turtle have focused on the physiological, biochemical, and molecular cascades initiated by the temperature signal. Both male and female development are active processes - rather than the crganized/default system characteristic of vertebrates with genotypic sex determination - that require simultaneous activation and suppression of testis- and ovary-determining cascades for normal sex determination. It appears that temperature accomplishes this end by acting on genes encoaing for steroidogenic enzymes and steroid hormone receptors and modifying the endocrine microenvironment in the embryo. The temperature experienced in development also has long-term functional outcomes in addition to sex determination. Research with the leopard gecko indicates that incubation temperature as well as steroid hormones serve as organizers in shaping the adult phenotype, with temperature modulating sex hormone action in sexual differentiation. Finally, practical applications of this research have emerged for the conservation and restoration of endangered egg-laying reptiles as well as the embryonic development of reptiles as biomarkers to monitor the estrogenic effects of common environmental contaminants. © 1994 Wiley-Liss, Inc.
    Additional Material: 14 Ill.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/dvg.1020150310
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  • 95
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    Developmental significance of epigenetic impositions on the plant genome: A paragenetic function for chromosomes (1994)
    Chichester [u.a.] : Wiley-Blackwell
    Developmental Genetics 15 (1994), S. 523-532 
    Details
    ISSN: 0192-253X
    Keywords: Epigenetic ; paramutation ; cosuppression ; pattern elaboration ; flower pigmentation ; plant morphogenesis ; Life and Medical Sciences ; Genetics
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Biology
    Notes: Developmental and physiological factors can impose heritable metastable changes on the plant genome, a fact that was established by maize geneticists during the 1950s and 1960s, largely through the efforts of R. Alexander Brink and Barbara McClintock. This paper describes a transgenic reporter system that monitors genomic impositions as changes in morphogenetically-determined flower color patterns. The observations reported here on the metastable properties of plant transgenes illustrate the proposals of Brink and McClintock that chromosomal impositions occur during normal development as ordered sequences of events which contribute to the elaboration of complex developmental patterns. The relationship between this process and some recent findings about the control of gene expression in transgenic plants is also discussed. © 1994 Wiley-Liss, Inc.
    Additional Material: 2 Ill.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/dvg.1020150611
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  • 96
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    A comparison of second-order and fourth-order pressure gradient algorithms in a σ-co-ordinate ocean model (1994)
    Chichester : Wiley-Blackwell
    International Journal for Numerical Methods in Fluids 18 (1994), S. 361-383 
    Details
    ISSN: 0271-2091
    Keywords: Boundary-fitted co-ordinates ; Stratified flow ; Hydrostatic pressure ; Engineering ; Engineering General
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Mechanical Engineering, Materials Science, Production Engineering, Mining and Metallurgy, Traffic Engineering, Precision Mechanics
    Notes: In stratified three-dimensional models the use of a boundary-fitted vertical co-ordinate is known to produce errors in the horizontal pressure gradient calculation near steep topography. The error is due to the splitting of the horizontal pressure gradient term in each of the momentum equations into two parts and the subsequent incomplete cancellation of the truncation errors of those parts. In order to minimize these pressure gradient errors, a fourth-order-accurate pressure gradient calculation has been implemented and installed in SPEM, a three-dimensional primitive equation ocean model. The stability and accuracy of the new scheme are compared with those of the original second-order-accurate model in a series of calculations of unforced flow in the vicinity of an isolated seamount. The new scheme is shown to have much smaller pressure gradient errors over a wide range of parameter space as well as a greater parametric domain of numerical stability.
    Additional Material: 14 Ill.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/fld.1650180404
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  • 97
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    Masthead (1994)
    Chichester : Wiley-Blackwell
    International Journal for Numerical Methods in Fluids 18 (1994) 
    Details
    ISSN: 0271-2091
    Keywords: Engineering ; Engineering General
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Mechanical Engineering, Materials Science, Production Engineering, Mining and Metallurgy, Traffic Engineering, Precision Mechanics
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/fld.1650180501
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  • 98
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    Adaptive panel methods and their integration with CAD (1994)
    Chichester : Wiley-Blackwell
    International Journal for Numerical Methods in Fluids 18 (1994), S. 747-760 
    Details
    ISSN: 0271-2091
    Keywords: Computer-aided design ; Adaptive methods ; Panel methods ; Computational fluid dynamics ; Engineering ; Engineering General
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Mechanical Engineering, Materials Science, Production Engineering, Mining and Metallurgy, Traffic Engineering, Precision Mechanics
    Notes: The work outlined below presents simple but effective adaptive meshing algorithms for boundary integral methods modelling inviscid flows (panel method) using the IGES standard for describing geometry. By using certain IGES entities in describing the boundary, CAD-derived geometry may be used such that the geometric integrity of the boundary is maintained after an adaptive redistribution of the mesh. Three types of error estimators are tested and all are shown to produce a more accurate representation of the flow phenomena for the same number of panels as compared with a uniform mesh distribution.
    Additional Material: 5 Ill.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/fld.1650180804
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  • 99
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    Conference diary (1994)
    Chichester : Wiley-Blackwell
    International Journal for Numerical Methods in Fluids 19 (1994), S. 269-270 
    Details
    ISSN: 0271-2091
    Keywords: Engineering ; Engineering General
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Mechanical Engineering, Materials Science, Production Engineering, Mining and Metallurgy, Traffic Engineering, Precision Mechanics
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/fld.1650190306
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  • 100
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    A method for finite element parallel viscous compressible flow calculations (1994)
    Chichester : Wiley-Blackwell
    International Journal for Numerical Methods in Fluids 19 (1994), S. 275-294 
    Details
    ISSN: 0271-2091
    Keywords: Navier-Stokes ; Fully-coupled solution ; Iterative solvers ; Finite-element methods ; Parallel algorithm ; Block diagonal preconditioning ; CFD ; Engineering ; Engineering General
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Mechanical Engineering, Materials Science, Production Engineering, Mining and Metallurgy, Traffic Engineering, Precision Mechanics
    Notes: This paper presents the parallelization aspects of a solution method for the fully coupled 3D compressible Navier-Stokes equations. The algorithmic thrust of the approach, embedded in a finite element code NS3D, is the linearization of the governing equations through Newton methods, followed by a fully coupled solution of velocities and pressure at each non-linear iteration by preconditioned conjugate gradient-like iterative algorithms. For the matrix assembly, as well as for the linear equation solver, efficient coarse-grain parallel schemes have been developed for shared memory machines, as well as for networks of workstations, with a moderate number of processors. The parallel iterative schemes, in particular, circumvent some of the difficulties associated with domain decomposition methods, such as geometry bookkeeping and the sometimes drastic convergence slow-down of partitioned non-linear problems.
    Additional Material: 15 Ill.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/fld.1650190402
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