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  • 1965-1969  (3)
  • 1945-1949
  • 1920-1924
  • 1966  (3)
  • Midbrain  (3)
  • 1
    Electronic Resource
    Electronic Resource
    Springer
    Experimental brain research 1 (1966), S. 184-194 
    ISSN: 1432-1106
    Keywords: Diurnal variation ; Pituitary-adrenal ; Corticosteroids ; Cortisol implants ; Hypothalamus ; Midbrain ; Ventral hippocampus
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary The effect of cortisol implants in the median eminence, midbrain reticular formation and ventral hippocampus has been assessed on basal adrenal activity. Two weeks after implantation rats were decapitated at 9–11 a m. or 4–5 p.m., and levels of adrenal and plasma corticosteroids were determined spectrofluorimetrically. Only implants in the median eminence produced a decrease in adrenal weight and a depression in a. m. adrenal corticosteroid levels. Implants in all three areas resulted in decreased levels of adrenal corticosteroids in the p. m. Implants in the ventral hippocampus and midbrain resulted in identical responses: plasma corticosteroids were increased in the a. m. and decreased in the p. m. Plasma corticosteroids were altered only in the p. m. following median eminence implants. The data indicate that the ventral hippocampus and midbrain are intimately involved in modulation of pituitary-adrenal function. It is suggested however, that cortisol implants in these areas may affect mechanisms in addition to those specifically related to pituitary-adrenal activity.
    Type of Medium: Electronic Resource
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  • 2
    Electronic Resource
    Electronic Resource
    Springer
    Experimental brain research 1 (1966), S. 205-219 
    ISSN: 1432-1106
    Keywords: D-C Potentials ; Hypothalamus ; Cortex ; Midbrain
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary D-C potential changes were evoked in the sensorimotor cortex and the hypothalamus of unanesthetized cats with chronically implanted electrodes by repetitive stimulation of the mesencephalic reticular formation. Stimulation at 30 to 300 p/sec. frequencies induced negative d-c shifts which were quite abrupt in onset, starting after the second or third shock with a peak of negativity reached within the first 50 to 100 msec of the 1 second duration of stimulation. Typically these negative shifts were sustained for the duration of stimulation with a prolonged 1 to 1.5 second return to baseline after termination of stimulation. Such d-c shifts were relatively independent of the site of the reference electrode but highly dependent on the location of the “active” recording electrodes and the stimulating electrodes. Reasons have been advanced to suggest that these negative d-c shifts reflect summated neuronal discharge in the immediate environs of “active” recording electrodes in the cerebral cortex and hypothalamus. In contrast to the consistent, stimulus-locked negative d-c shifts, less consistent changes, usually positive in polarity, were observed to begin 2 to 3 seconds after termination of RF stimulation. These slower d-c changes were highly dependent on the site of the reference electrode and the physical state of tissue at the electrode tip and therefore far less directly related to neuronal events in cortical and hypothalamic tissue.
    Type of Medium: Electronic Resource
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  • 3
    ISSN: 1432-1106
    Keywords: Squirrel monkey ; Midbrain ; Histochemical mapping ; Succinic dehydrogenase ; Cytochrome oxidase
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary The distribution of succinic dehydrogenase (SDA) and cytochrome oxidase (Cy. O) has been investigated in a series of sections through the pons and mesencephalon of the squirrel monkey brain. The localization of the two enzymes is very similar in the various regions and shows only slight differences. The epiphysis, however, shows moderately strong SDA and very mild Cy. O activity. Particularly strong SDA and Cy. O activity has been observed in the cell bodies of the various cranial nerve nuclei, nucleus colliculi inferioris, colliculi superioris, nuclei griseum pontis, reticularis tegmenti pontis, lemnisci lateralis pars dorsalis, geniculatum laterale and mediale, and pulvinaris. The enzyme content of the neurons and cell bodies is generally stronger compared to the neuropil which often occurs in smooth, loose, compact and reticulated forms. Any special relationship between the neurons and neuropil with regard to their enzyme content has, however, not been observed. The cranial nerves, and fibers of the brachium conjunctivum, corpus callosum, and fornix show very mild enzyme activity except those of the trapezoid complex which show moderate enzyme activity.
    Type of Medium: Electronic Resource
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