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Digitale Medien

Averages of glutamine synthetase molecules as obtained with various stain and electron dose conditions (1980)

Kessel, M. ; Frank, J. ; Goldfarb, W.

New York, N.Y. : Wiley-Blackwell

Journal of Supramolecular Structure 14 (1980), S. 405-422

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Details

ISSN: 0091-7419

Schlagwort(e): glutamine synthetase ; electron microscopy ; computer averaging ; pattern recognition ; radiation damage ; low dose ; Life Sciences ; Molecular Cell Biology

Quelle: Wiley InterScience Backfile Collection 1832-2000

Thema: Biologie , Chemie und Pharmazie , Medizin

Notizen: Averaged projections of individual glutamine synthetase molecules have been obtained by using electron microscopy and image processing. The methodology of correlation averaging under low dose conditions is described in detail. Because of their low signal-to-noise ratio, images made under low dose conditions cannot be directly interpreted in terms of high resolution features. Computer averaging of these images reveals a division of the subunit projection into two domains whose sizes agree with results of Lei et al [2] limited proteolysis experiments.

Zusätzliches Material: 10 Ill.

Materialart: Digitale Medien

URL: http://dx.doi.org/10.1002/jss.400140402

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