ISSN:
0003-276X
Keywords:
Life and Medical Sciences
;
Cell & Developmental Biology
Source:
Wiley InterScience Backfile Collection 1832-2000
Topics:
Medicine
Notes:
Maternal pteroylglutamic acid (PGA or folic acid) deficiency from the ninth to eleventh days of gestation produced in rat fetuses a variety of congenital abnormalities of the pulmonary and other vessels. These included single pulmonary artery, absence of the ductus arteriosus, single coronary artery, stenosis of the pulmonary trunk, persistent truncus arterious, and termination of the pulmonary veins in the right atrium or left anterior vena cava. Study of young PGA-deficient embryos showed a number of these anomalies in the course of development. Many of the abnormalities encountered resembled those occurring in man.
Additional Material:
22 Ill.
Type of Medium:
Electronic Resource
URL:
http://dx.doi.org/10.1002/ar.1091470311