ZIB

Hits per page

hit 1 - 1 | 1 hit

Select All Export

Electronic Resource

First Total Synthesis of Enantiomerically Pure(-)-Silphiperfol-6-en-5-onFor a Preliminary communication of this work, see [1a,b][2]. (1988)

Demuth, Martin ; Hinsken, Werner

New York, NY : Wiley-Blackwell

Helvetica Chimica Acta 71 (1988), S. 569-576

add to mindlist on the mindlist

Details

ISSN: 0018-019X

Keywords: Chemistry ; Organic Chemistry

Source: Wiley InterScience Backfile Collection 1832-2000

Topics: Chemistry and Pharmacology

Notes: The angular triquinane (-)-silphiperfol-6-en-5-on ((-)-14) has been synthesized for the first time time in enantiomerically pure form. A highly efficient triplet-sensitized photoreaction, the oxadi-π-methane rearrangement of the complex β,γ-enone(+)-6 to (-)-7, constitutes the key step. The know staring material, (1R, 7aR)-3,6,7,7a-tetrahydro-1-hydroxy-7a-methyl-1H-inden-5(2H)-one ((-)-2), is readily accessible in 〉 97% enantiomeric purity. This new approach should enable access also to other angularly fused triquinanes of the silphinene type and related structures.

Type of Medium: Electronic Resource

URL: http://dx.doi.org/10.1002/hlca.19880710309

Library	Location	Call Number	Volume/Issue/Year	Availability

Others were also interested in ...

Paper (German National Licenses)

Fulltext

hit 1 - 1 | 1 hit