ISSN:
0899-0042
Keywords:
organogels
;
reversed micelles
;
Aerosol-OT
;
lipase
;
2-methylbutyric acid
;
ethyl-2-methylbutyrate
;
enantioselective reaction resolution
;
Chemistry
;
Organic Chemistry
Source:
Wiley InterScience Backfile Collection 1832-2000
Topics:
Chemistry and Pharmacology
Notes:
Chromobacterium viscosum lipase (c.v. lipase) was immobilized in microemulsion-based órganogels and successfully utilized for the enantioselective esterification of (+/-)-2-methylbutynic acid to preferentially form ethyl-(+)-2-methylbutyrate. The reaction time course and enantioselectivity obtained with the organogel - lipase system was compared and contrasted to that achieved in a reversed micellar solution system that contained lipase solubilized in its inner water core as well as that in which powdered lipases were directly dispersed in an organic solvent. The unique properties and potential benefits of the organogel system are discussed. © 1994 Wiley-Liss, Inc.
Additional Material:
4 Ill.
Type of Medium:
Electronic Resource
URL:
http://dx.doi.org/10.1002/chir.530060808
