Electronic Resource
Springer
European archives of oto-rhino-laryngology and head & neck
253 (1996), S. 501-503
ISSN:
1434-4726
Keywords:
Deafness
;
Otosclerosis
;
HLA antigens
Source:
Springer Online Journal Archives 1860-2000
Topics:
Medicine
Notes:
Abstract Otosclerosis is a disease of the otic capsule that is caused by abnormal resorption and redeposition of bony tissue. Sixty-two unrelated Japanese patients exhibiting clinical otosclerosis were typed for HLA-A, -B,-C antigens. Twenty-one of the patients were also typed for DR antigens. The frequency of HLA-Aw33 was significantly higher in otosclerosis patients than in the control group (24.2% vs 9.5%). This finding suggests that the presence of HLA-Aw33 antigens may be related to an increased susceptibility to otosclerosis or to its clinical outcome.
Type of Medium:
Electronic Resource
URL:
http://dx.doi.org/10.1007/BF00179958
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