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Phospholipids in pulmonary alveolar proteinosis (1974)

Einolf, W. Noel ; Fenselau, Catherine

Chichester : Wiley-Blackwell

Biological Mass Spectrometry 1 (1974), S. 195-198

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ISSN: 1052-9306

Keywords: Chemistry ; Analytical Chemistry and Spectroscopy

Source: Wiley InterScience Backfile Collection 1832-2000

Topics: Chemistry and Pharmacology

Notes: Gas chromatography-mass spectrometry has been used to identify the phosphate diester backbones of two classes of phospholipids previously unrecognized in washings from human lungs. Washings were analyzed from two patients with pulmonary alveolar proteinosis and also from two pairs of normal lungs washed postmortem. α-Glycerophosphorylglycerol and α-glycerophosphorylinositol were identified in all four cases following hydrolysis of the fatty acid esters and treatment with trimethylsilylating reagent.

Additional Material: 5 Ill.

Type of Medium: Electronic Resource

URL: http://dx.doi.org/10.1002/bms.1200010310

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