ISSN:
0030-493X
Keywords:
Chemistry
;
Analytical Chemistry and Spectroscopy
Source:
Wiley InterScience Backfile Collection 1832-2000
Topics:
Chemistry and Pharmacology
Notes:
The mass spectra of several 4,5-disubstituted-2-oxazolidones and several related N-methyl derivatives have been determined. Fragmentation has been found to be a function of three factors: (1) the size of the alkyl function at C-5, (2) the location of the aryl substituent, and (3) replacement of N—H by N—CH3. In particular, aryl or bulky alkyl groups substituted at C-5 result in protonated aldehyde derived from hydrogen rearrangement from nitrogen. With other substituents, the most intense ions are nitrogen containing fragments. In the latter case the fragmentation pathway has been elucidated with the aid of metastable peaks observed using defocusing techniques.
Additional Material:
8 Ill.
Type of Medium:
Electronic Resource
URL:
http://dx.doi.org/10.1002/oms.1210040105
