ISSN:
0030-493X
Keywords:
Chemistry
;
Analytical Chemistry and Spectroscopy
Source:
Wiley InterScience Backfile Collection 1832-2000
Topics:
Chemistry and Pharmacology
Notes:
The structures of kikumycin A and B, antiviral amidine antibiotics, have been elucidated by means of low and high resolution mass spectrometry. Amino acid composition and their sequences were also clearly demonstrated by this technique. The evidence for the fragmentation of terminal amidines or amides of kikumycin derivatives and related synthetic compounds was represented by the elimination of ammonia or water from the molecular ions to give stable nitrile ions. Additionally, the participation of the iminol structure in the pyrrole-2-carboxamide portion of kikumycin A and B was confirmed by the fragment ions derived from their iminol tautomers.
Additional Material:
4 Ill.
Type of Medium:
Electronic Resource
URL:
http://dx.doi.org/10.1002/oms.1210090703