ISSN:
0749-1581
Keywords:
13C NMR
;
4,5-Dihydroisoxazoles
;
Substituent effects
;
Heterocycles
;
Chemistry
;
Analytical Chemistry and Spectroscopy
Source:
Wiley InterScience Backfile Collection 1832-2000
Topics:
Chemistry and Pharmacology
Notes:
Evaluation by empirically derived equations for the substituent effect (α, β, γ, δ) on the 13C NMR chemical shifts for C-3, C-4, C-5 and halomethyl-substituent carbon (C-6) in 5-halomethyl-5-hydroxy-4,5-dihydroisoxazoles (where C-3 substituent=H), alkyl or phenyl, C-4 substituent=H, alkyl or heteroalkyl and C-5 substituent (=dior trihalomethyl), taking as reference 5-trichloromethyl-5-hydroxy-4,5-dihydroisoxazole, is reported. From the calculated values for the α, β, γ and δ effects for each substituent it was possible to estimate the chemical shift of each carbon of the compounds.
Additional Material:
2 Tab.
Type of Medium:
Electronic Resource
URL:
http://dx.doi.org/10.1002/mrc.1260321009
