ISSN:
0001-1541
Keywords:
Chemistry
;
Chemical Engineering
Source:
Wiley InterScience Backfile Collection 1832-2000
Topics:
Chemistry and Pharmacology
,
Process Engineering, Biotechnology, Nutrition Technology
Notes:
The mechanism by which oxygen is transported from capillaries into tissue for cell respiration has been a subject of interest since the work of August Krogh in 1919. Mathematical analyses of the diffusion process have been obtained by several investigators (11, 12, 18), but are limited in scope by the complicated nature of the problem. However, the solutions that exist give enough insight to inspire a more rigorous treatment. With the advant of electronic computers more complete analyses are now within reach (16).The human brain accounts for less than 4% of the total body weight, yet it uses 15 to 20% of the total body oxygen consumption. This high metabolic rate makes the brain particularly vulnerable to any change in the normal oxygen supply. The fact that following a cessation of cerebral blood flow, unconsciousness develops within 10 sec., and irreversible damage within 10 min., demonstrates the importance of understanding the dynamics of oxygen supply to the brain.
Additional Material:
12 Ill.
Type of Medium:
Electronic Resource
URL:
http://dx.doi.org/10.1002/aic.690150620
