ISSN:
0006-3525
Keywords:
Chemistry
;
Polymer and Materials Science
Source:
Wiley InterScience Backfile Collection 1832-2000
Topics:
Chemistry and Pharmacology
Notes:
Water-soluble polypeptides of L-valyl and L-isoleucyl residues flanked with DL-lysyl blocks [poly(DLLys · HCl)x-poly(LVal)y-poly(DLLys · HCl)x, poly(DLLys · HCl)x-poly-(LIle)y-poly(DLLys · HCl)x] and homopoly(L-threonine) were prepared. The β conformation of these polymers in water, as well as in aqueous methanol, was confirmed by infrared spectroscopy and circular dichroism studies. The optical properties of these valyl and isoleucyl polypeptides were quite different from those of previously reported synthetic homopolypeptides in the β structure. Their differences could be explained by the presence of a “single extended β chain” without either intra- or interchain association.
Additional Material:
9 Ill.
Type of Medium:
Electronic Resource
URL:
http://dx.doi.org/10.1002/bip.1975.360140314