ISSN:
0006-3525
Keywords:
Chemistry
;
Polymer and Materials Science
Source:
Wiley InterScience Backfile Collection 1832-2000
Topics:
Chemistry and Pharmacology
Notes:
(DLLys)10-(LVal)20-(DLLys)10, a copolymer of a valine block in the β conformation with randomly coiled flanking blocks of lysine [Kubota, S. & Fasman, G. D. (1975) Biopolymers 14, 605-631], was studied by nuclear magnetic resonance. The peak areas of the N—H and C—H resonances of valine and lysine are concentration-dependent with little chemical shift change. A model is presented describing the aggregation of the copolymer. Additional evidence, obtained by monitoring the spin-lattice relaxation times of amino, amide, γ-methyl-valine, and ∊-methylene-lysine, is consistent with the aggregation model. Hydrodynamic studies are presented which show monomer → oligomer aggregation of four or five subunits.
Additional Material:
7 Ill.
Type of Medium:
Electronic Resource
URL:
http://dx.doi.org/10.1002/bip.1976.360150711
