ISSN:
0006-3592
Keywords:
Chemistry
;
Biochemistry and Biotechnology
Source:
Wiley InterScience Backfile Collection 1832-2000
Topics:
Biology
,
Process Engineering, Biotechnology, Nutrition Technology
Notes:
The effect of regularly varying the input nutrient concentration on the growth and composition (elemental and macromolecular) of Escherichia coli ML30 grown in chemostat culture is reported. After each change in substrate concentration a lag between the stimulus and organism response occurred, the magnitude of which was dependent upon the frequency of the perturbations. Both the growth yield and macromolecular composition of the cells were found to vary with the frequency of nutrient cycling: the yield decreased by some 10% as the cycle-times decreased from 6.0 to 0.25 hr. It is suggested that maintaining microorganisms under controlled transient conditions might be useful in increasing yields of specific microbial products (e.g., single-cell protein).
Additional Material:
5 Ill.
Type of Medium:
Electronic Resource
URL:
http://dx.doi.org/10.1002/bit.260210609
