ISSN:
0009-286X
Keywords:
Chemistry
;
Polymer and Materials Science
Source:
Wiley InterScience Backfile Collection 1832-2000
Topics:
Chemistry and Pharmacology
,
Process Engineering, Biotechnology, Nutrition Technology
Notes:
Scale-up under conditions of partial similarity. When appropriate physical properties of the system are not available, it is impossible to accurately simulate the working conditions of an industrial plant in a laboratory-scale experiment, and it then becomes necessary to resort to experiments under conditions of partial similarity. In these cases the laboratory-scale experiments must be carried out in devices of various sizes and the results extrapolated to the industrial-scale conditions. This expensive and inevitably unreliable procedure can occasionally be substituted by a systematic experimental approach based on dividing the process in question into individual parts which are then investigated separately (Examples 1 and 3), or by deliberately abandoning certain similarity criteria and checking the subsequent effects on the process as a whole (Example 2). In mixing technology, volume-related mixing power is often taken as the scale-up criterion, while in the design of bubble columns, the superficial velocity of the gas is taken as a basis. Both these cases are examples of scale-up under conditions of partial similarity, and their validity is subjected to a critical examination (Examples 4 and 5).
Additional Material:
3 Ill.
Type of Medium:
Electronic Resource
URL:
http://dx.doi.org/10.1002/cite.330570506
