ISSN:
0749-503X
Keywords:
Yeast
;
Saccharomyces cerevisiae
;
chromosome II
;
polymerase α-primase
;
cyclohydrolase II
;
ribA
;
DNA sequencing
;
Life and Medical Sciences
;
Genetics
Source:
Wiley InterScience Backfile Collection 1832-2000
Topics:
Biology
Notes:
The DNA sequence of two contiguous 7648 bp and 1194 bp BamHI fragments from the cosmid α1201 located about 60 kb from the centromere on the left arm of chromosome II from Saccharomyces cerevisiae has been determined. Sequence analysis reveals four new open reading frames longer than 300 bp: YBL0415 (309 bp), YBL0416 (4539 bp). YBL0417 (1035 bp) and YBL0414 (2115 bp), which extends into the neighbouring 5·2 kb BamHI fragment. The YBL0414 shows homologies to the mouse 68 kDa and Drosophila melanogaster 76 kDa subunits of the DNA polymerase α-primase complex. The YBL0417 is homologous to bacterial GTP cyclohydrolase II (EC 3.5.4.25). The sequence has been deposited in the EMBC data library under Accession Number X74738.
Additional Material:
5 Ill.
Type of Medium:
Electronic Resource
URL:
http://dx.doi.org/10.1002/yea.320100003