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  • 1
    Electronic Resource
    Electronic Resource
    Hoboken, NJ : Wiley-Blackwell
    Journal of Biomedical Materials Research 4 (1970), S. 107-119 
    ISSN: 0021-9304
    Keywords: Chemistry ; Polymer and Materials Science
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Medicine , Technology
    Notes: Composite hydrophilic materials (CHM) containing collagen or cellulose as the insoluble fibrous component and potassium salts of proteinpolysaccharide or carboxymethylcellulose as the soluble polyelectrolyte were prepared as simple models of the connective tissue, cartilage. The tensile properties of uncrosslinked and formaldehyde-crosslinked collagenous CHM were measured and compared to those of bovine nasal cartilage (BNC). The compressive properties of uncrosslinked and formaldehyde-crosslinked cellulosic CHM were measured and compared to bovine nasal cartilage. Although elongating to approximately the same extent before breaking (20%), the uncrosslinked collagenous CHM had lower tensile strengths than BNC (330 psi). Formaldehyde crosslinking increased the tensile strength of the collagenous CHM to as much as 3 times that of BNC but reduced the elongation at failure to only 7%. The uncrosslinked cellulosic CHM attained a maximum of only ¼ the compressive strength of BNC (940 psi). Formaldehyde crosslinking extended the compressive strength to as high as ⅓ that of BNC. The results indicate that the simple uncrosslinked and crosslinked models can only partially account for the mechanical properties of BNC.
    Additional Material: 3 Tab.
    Type of Medium: Electronic Resource
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