ISSN:
0570-0833
Keywords:
Carboxylic acids
;
1,1-Dichloroethylene
;
Synthetic methods
;
Chemistry
;
General Chemistry
Source:
Wiley InterScience Backfile Collection 1832-2000
Topics:
Chemistry and Pharmacology
Notes:
Many β-alkyl- and β-arylpropionic acids are readily obtainable by the reaction of secondary or tertiary alcohols, esters of these, or olefins with the inexpensive 1, 1-dichloroethylene in sulfuric acid. The success of the synthesis depends on the bulk and energy of the carbonium ion intermediate formed from the alcohols or olefins. With carbonium ions having one H atom attached to the carbonium C atom, electrophilic substitution of the 1,1-dichloroethylene takes place to a small extent. Dicarboxylic acids and carboxylic acids with higher molecular weights are sometimes formed as a result of side reactions.
Additional Material:
2 Tab.
Type of Medium:
Electronic Resource
URL:
http://dx.doi.org/10.1002/anie.196608701