ISSN:
0362-2525
Keywords:
Life and Medical Sciences
;
Cell & Developmental Biology
Source:
Wiley InterScience Backfile Collection 1832-2000
Topics:
Biology
,
Medicine
Notes:
Total splenectomy in the frog means practically complete extirpation of the erythropoietic apparatus. Out of sixty-four operations it was followed by: 1Stimulation of erythropoiesis in the kidney (mesonephros), 35 to 46 per cent.2Stimulation of erythropoiesis in the fat-bodies, 5 per cent; lymphocytopoiesis, 8 per cent.3Stimulation of erythropoiesis in the bone-marrow, 11 per cent.4Formation of a new spleen, 8 per cent.5No perceptible erythropoletic stimulation, 24 per cent. The latter leads to a condition of anemia followed by death within about sixty days.Partial splenectomy leads to spleen regeneration.The life tenure of the frog erythrocyte is approximately 100 days.Total splenectomy experiments indicate that the chief function of the spleen in the frog inheres largely in its lymphocyte content and in the transformation of lymphocytes into erythrocytes.
Additional Material:
4 Ill.
Type of Medium:
Electronic Resource
URL:
http://dx.doi.org/10.1002/jmor.1050400303
