ISSN:
0003-276X
Keywords:
Life and Medical Sciences
;
Cell & Developmental Biology
Source:
Wiley InterScience Backfile Collection 1832-2000
Topics:
Medicine
Notes:
Dorsal roots from adult rabbits prepared by a freeze-substitution technique and studied by electron microscopy have been compared with those obtained by standard fixation with OsO4. The essential features of myelinated and nonmyelinated fibers and their associated Schwann cells are similar in appearance after both types of fixation. There are, however, slight differences. The extracellular clefts between the nonmyelinated axons and their associated Schwann cells are wider in freeze-substituted roots (200 to 250 Å versus 100 to 150 Å). The major dense lines in the myelin sheath are wider (45 to 55 Å versus about 30 Å) and their radial repeat period is larger (145 to 155 Å versus 100 to 120 Å) in freeze - substituted material than in routinely fixed nerves.
Type of Medium:
Electronic Resource
URL:
http://dx.doi.org/10.1002/ar.1091520308
