ISSN:
0003-276X
Keywords:
Life and Medical Sciences
;
Cell & Developmental Biology
Source:
Wiley InterScience Backfile Collection 1832-2000
Topics:
Medicine
Notes:
The development of the folial patterns of the human cerebellar vermis has been studied in 44 mid sagittal sections of fetuses (14 weeks gestational age to term), infants (one to three months) and adults. The differentiation of each of the lobules of the vermis has been plotted as a function of age. The gestational age at which each lobule has attained half the adult average number of folia has been determined and varies between 24 and 37 weeks; the more anterior and posterior vermian lobules reach this half-way point first even though the largest lobules (culmen, declive and pyramis) form more folia per unit time. Thus, different criteria may be used to evaluate growth rates and yield different conclusions concerning the validity of the concept that ontogeny recapitulates phylogeny. The adult numbers of folia are not attained until more than two months after birth. The normative data reported in this study provide a baseline for comparison with other species or with abnormal developmental patterns in autopsy specimens of any fetal or post-natal age.
Additional Material:
3 Ill.
Type of Medium:
Electronic Resource
URL:
http://dx.doi.org/10.1002/ar.1091730109