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Photodynamic and fluorochromic properties of the antibiotic actinomycin D (1965)

Zhdanov, Victor M. ; Yershov, Felix I.

Philadelphia : Wiley-Blackwell

Journal of Cellular and Comparative Physiology 65 (1965), S. 433-434

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ISSN: 0095-9898

Keywords: Life and Medical Sciences ; Cell & Developmental Biology

Source: Wiley InterScience Backfile Collection 1832-2000

Topics: Biology , Medicine

Notes: Actinomycin D was studied as a photodynamic agent and fluorochrome. With Venezuelan equine encephalitis virus propagated in chick fibroblasts, it was shown that actinomycin D induces both direct and indirect photoactivation of the virus. Some capacity of antibiotic-treated and irradiated virus to produce plaques larger than usual was not retained with passage of virus isolated from large plaques. Cells stained with actinomycin D exhibited a weak brownish fluorescence of nuclear structure.

Additional Material: 1 Tab.

Type of Medium: Electronic Resource

URL: http://dx.doi.org/10.1002/jcp.1030650317

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