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Cell locomotion: New research tests old ldeas on membrane and cytoskeletal flow (1991)

Heath, Julian P. ; Holifield, Bruce F.

New York, NY : Wiley-Blackwell

Cell Motility and the Cytoskeleton 18 (1991), S. 245-257

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ISSN: 0886-1544

Keywords: lipid flow ; cytoskeleton ; actin ; microscopy ; Life and Medical Sciences ; Cell & Developmental Biology

Source: Wiley InterScience Backfile Collection 1832-2000

Topics: Biology , Medicine

Notes: Recent studies on the mobility of membrane markers on crawling cells indicate that there is no long-range centripetal flow of membrane proteins or lipids during cell locomotion. In this article we reflect on the history of ideas about membrane flow in cells, and we discuss how these new findings will shift the focus of research in cell locomotion away from the cell surface to the molecular interactions and dynamics of the actin cytoskeleton.

Additional Material: 4 Ill.

Type of Medium: Electronic Resource

URL: http://dx.doi.org/10.1002/cm.970180402

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