ISSN:
0947-3440
Keywords:
Bimacrocycle
;
Base catalysis
;
Hydrogen bond
;
Molecular recognition
;
Pyridine
;
Chemistry
;
Organic Chemistry
Source:
Wiley InterScience Backfile Collection 1832-2000
Topics:
Chemistry and Pharmacology
Notes:
Concave pyridines 1 were used to catalyze the addition of primary and secondary alcohols to ketenes 4, and the kinetic data of these catalyses were determined. In inter- and intramolecular competitions the use of 1e-g led to improved selectivities for the acylation of primary alcohols in comparison with secondary alcohols. All primary alcohols react at comparable rates. Observed rate constants were correlated with Taft's Es values. The starting materials and products were fully characterized.
Additional Material:
2 Ill.
Type of Medium:
Electronic Resource
URL:
http://dx.doi.org/10.1002/jlac.199619961223
