ISSN:
0009-2940
Keywords:
Chemistry
;
Inorganic Chemistry
Source:
Wiley InterScience Backfile Collection 1832-2000
Topics:
Chemistry and Pharmacology
Notes:
Chloroquine Enantiomers by Chromatographic Resolution and SynthesisThe chromatographic resolution of the antimalarial drug chloroquine (1) on an optically active polyamide is described. The results reveal that the optical purity of chloroquine formerly resolved with d-bromocamphorsulfonic acid was 12% only. A facile synthesis of the enantiomers via the optically active diamine 4 is given.
Type of Medium:
Electronic Resource
URL:
http://dx.doi.org/10.1002/cber.19781110730