ISSN:
0009-2940
Keywords:
Bicyclo[2.2.1]heptanes
;
Tricyclo[5.2.1.02,6]decanes
;
Norbornanes
;
Ozonization
;
Cage compounds
;
Chemistry
;
Inorganic Chemistry
Source:
Wiley InterScience Backfile Collection 1832-2000
Topics:
Chemistry and Pharmacology
Notes:
A four-step preparation of dimethyl 7-oxobicyclo[2.2.1]-heptane-exo-2, exo-3-dicarboxylate (4) in satisfactory yield from the readily available 6,6-dimethylfulvene and maleic anhydride is described. Compound 4 represents a well-functionalized intermediate for the synthesis of norbornane derivatives which is used for an improved synthesis of the tricyclic diester 7, precursor of the cage compound 8. An alternative approach to diester 7 from dimethyl 7-isopropylidenebicyclo[2.2.1]heptane-exo-2, exo-3-dicarboxylate (2) is also discussed.
Additional Material:
1 Ill.
Type of Medium:
Electronic Resource
URL:
http://dx.doi.org/10.1002/cber.19901230824