ISSN:
0075-4617
Keywords:
Chemistry
;
Organic Chemistry
Source:
Wiley InterScience Backfile Collection 1832-2000
Topics:
Chemistry and Pharmacology
Description / Table of Contents:
Preparation of Radioactive Organic Compounds, II. L-3-Methoxy[3H]-ωM-[1-hydroxy-1-phenyl-isopropylamino]-propiophenone Hydrochloride2)3H-Methyliodide (1) is used for the methylation of m-methoxy[3H]-acetophenone (2). The resulting radiochemically pure m-methoxy[3H]-acetophenone (3) with formaldehyde and 1-norephedrine (4) gives the title compound 5. Following the course of this Mannich reaction by thinlayer chromatography and radiometric measurements, it is shown that 3 cannot be transformed completely into 5.
Notes:
Methyljodid-[3H] (1) wird im Überschuß zur Methylierung von m-Hydroxy-acetophenon (2) eingesetzt. Das erhaltene, radiochemisch reine m-Methoxy-[3H]-acetophenon (3) gibt mit Formaldehyd und 1-Norephedrin (4) die Titelverbindung 5.
Type of Medium:
Electronic Resource
URL:
http://dx.doi.org/10.1002/jlac.19717450104
