ISSN:
1434-193X
Keywords:
1,3,2-Benzothiaselenazole 1,1-dioxides
;
Cytokine inducers
;
Diselenobis(benzenesulfonamides)
;
Diselenides
;
Sulfonamides
;
Chemistry
;
General Chemistry
Source:
Wiley InterScience Backfile Collection 1832-2000
Topics:
Chemistry and Pharmacology
Notes:
-A convenient method for the synthesis of 2,2′-diselenobis(benzenesulfonamides) 4 and 2-substituted 1,3,2-benzothiaselenazole 1,1-dioxides 2, has been elaborated. It is based on the conversion of 2-aminobenzenesulfonic acid into bis[2-(chlorosulfonyl)phenyl] diselenide (6), and reaction with ammonia or primary amines to give the sulfonamides 4. Finally, cyclization of these sulfonamides by oxidation with benzoyl peroxide or by treatment of their sodium or potassium salt with elemental bromine produces 1,3,2-thiaselenazole 1,1-dioxides 2.
Type of Medium:
Electronic Resource
