ISSN:
0170-2041
Keywords:
Biaryls, ether-type bridged, preparation and stereostructure of
;
X-ray crystallography
;
Chemistry
;
Organic Chemistry
Source:
Wiley InterScience Backfile Collection 1832-2000
Topics:
Chemistry and Pharmacology
Notes:
A simple two-step synthesis of a series of ether-type bridged biaryls 3, as favorable models for studies of helimerization processes, is described. Starting from the known corresponding lactones 1, a variety of differently substituted representatives 3 is prepared, greatly varying by the degree of steric hindrance and thus molecular distortion. NMR spectroscopy and especially X-ray diffraction reveal the ethers 3 to be helically distorted, depending on the size of the ortho substituents R.
Additional Material:
2 Ill.
Type of Medium:
Electronic Resource
URL:
http://dx.doi.org/10.1002/jlac.1992199201127