ISSN:
0941-1216
Keywords:
Chemistry
;
Organic Chemistry
Source:
Wiley InterScience Backfile Collection 1832-2000
Topics:
Chemistry and Pharmacology
Notes:
Synthesis of Spirocyclic Isothiazolium Salts and their Base Catalysed Reaction to ThianthrenesN-Phenyl-substituted isothiazolium salts 1 with active 7-methylene group react under the influence of bases to the spirocyclic isothiazolium salts rac-cis- and rac-trans-4; the salts trans-4 are not stable and react to the thianthrene derivatives rac-trans-6. Thus, a very simple separation of diastereoisomeric salts rac-cis- and rac-trans-4 is possible. The influence of donor and acceptor substituents in the phenyl group of 1 on the diastereoselective synthesis of 4 and 6 was studied. The structure of rac-cis-4 and rac-trans-6 was confirmed by X-ray analysis.
Additional Material:
2 Ill.
Type of Medium:
Electronic Resource
URL:
http://dx.doi.org/10.1002/prac.19963380183