ISSN:
0941-1216
Keywords:
Chemistry
;
Organic Chemistry
Source:
Wiley InterScience Backfile Collection 1832-2000
Topics:
Chemistry and Pharmacology
Notes:
Twofold Ring Cleavage of 2,3,5,6-Tetrahydro-10bH-oxazolo[2,3-a]isoquinoline with Salts of Hydroxylamine DerivativesContrary to literature the reaction of the cyclic carbinolamine ether 1 with hydroxylamine hydrochloride don't give the N-hydroxyaminal hydrochloride 2· HCl, but the ring opened E-oxime amine hydrochloride 3· HCl. The structure is proved with NMR- and UV-spectroscopic methods. Similar products 11· HCl -15· HCl and 18· HCl/19 · HCl are available from salts of hydroxylamine ethers and semicarbazides. The reactivity of 1 and the stability of the products are investigated.
Type of Medium:
Electronic Resource
URL:
http://dx.doi.org/10.1002/prac.199633801140