ISSN:
0268-2605
Keywords:
arsenic
;
arsenobetaine
;
microorganisms
;
uptake
;
degradation
;
conversion
;
trimethylarsine oxide
;
dimethylarsinic acid
;
inorganic arsenic
;
Chemistry
;
Organic Chemistry
Source:
Wiley InterScience Backfile Collection 1832-2000
Topics:
Chemistry and Pharmacology
Notes:
We have reported the degradation of arsenobetaine [(CH3)3As+CH2COO-] to inorganic arsenic by microorganisms from various marine origins such as sediments. However, there was no information as to the fate of the ingested arsenobetaine within the body of the microorganisms before excretion.In this study, arsenobetaine and sediments were added to two culture media (1/5 Zobell 2216E and a solution of inorganic salts) and aerobically incubated at 25°C in the dark. Despite the degradation and complete disappearance of arsenobetaine from the filtrates of the incubation mixtures, the major arsenic compound from the microorganisms harvested from the mixtures was identified by HPLC as arsenobetaine throughout the incubation period. The presence of arsenobetaine was further confirmed by TLC and fast atom bombardment mass spectrometry (FAB MS). A minor arsenical also present in the incubated microorganisms, dimethylarsinic acid, was detected.
Additional Material:
4 Ill.
Type of Medium:
Electronic Resource
URL:
http://dx.doi.org/10.1002/aoc.590090712
