ISSN:
0018-019X
Keywords:
Chemistry
;
Organic Chemistry
Source:
Wiley InterScience Backfile Collection 1832-2000
Topics:
Chemistry and Pharmacology
Notes:
Human plasma or serum is desalted completely by passing through a column containing a suitable mixture of an anion exchanger (OH-cycle) and a cation exchanger (H+ cycle). At the resulting very low ionic strength and pH 5.2 part of the globulins is precipitated. The solution is neutralized. A stabilizer such as sodium caprylate and glucose if necessary to make an isotonic solution are added. Then the solution is filtered through a bacterial filter into the final containers. It can be pasteurized for 10 hours at 60° C without clotting, a treatment known to kill the homologous serum hepatitis virus which is frequently present in pooled plasma.
Additional Material:
2 Ill.
Type of Medium:
Electronic Resource
URL:
http://dx.doi.org/10.1002/hlca.19540370622
