ISSN:
0018-019X
Keywords:
Chemistry
;
Organic Chemistry
Source:
Wiley InterScience Backfile Collection 1832-2000
Topics:
Chemistry and Pharmacology
Notes:
The aminolysis of two penicillin-like compounds which cannot form penicillenic acid has been studied: 16-Aminopenicillanic acid (which is highly immunogenic) reacts directly with ε-amino groups at pH 7,4 under CO2-free conditions; the possible role of its polymerisation in this reaction remains to be studied.26-Dinitrophenylamino-penicillanic acid reacts with εamino groups at pH 7,4 as fast as benzylpenicillin and other penicillins. Its immunogenicity in the rabbit is similar to that of benzylpenicillin.
Type of Medium:
Electronic Resource
URL:
http://dx.doi.org/10.1002/hlca.19660490533