ISSN:
0018-019X
Keywords:
Chemistry
;
Organic Chemistry
Source:
Wiley InterScience Backfile Collection 1832-2000
Topics:
Chemistry and Pharmacology
Notes:
It has been stated in a preceding paper [3] that only parts of a ligand coordinated to a metal ion can be oxidized by H2O2 (= peroxidative activity). Considering the reversal of this statement to be true, it is shown by means of the peroxidative activity of the Cu2+-complexes of ATP, ITP, CTP, UTP, and TTP that in these complexes the heteroaromatic groups contribute to the coordination of Cu2+ ion. By analogy with the Cu2+-ATP-complex, where a macrocyclic phosphate-metal-adenine chelate is formed [4], and based on his experimental results, the author considers the existence of such a macrocyclic chelate in the copper complexes of ITP, GTP, CTP, UTP, and TTP as established. The coordination sites of the heteroaromatic groups in these complexes are discussed.
Additional Material:
3 Ill.
Type of Medium:
Electronic Resource
URL:
http://dx.doi.org/10.1002/hlca.19670500223
