ISSN:
0018-019X
Keywords:
Chemistry
;
Organic Chemistry
Source:
Wiley InterScience Backfile Collection 1832-2000
Topics:
Chemistry and Pharmacology
Notes:
The total or partial structure determinations of some new components from Dregea abyssinica are reported. The four drebyssogenins (F, G, J and H) are esters of the drevogenins P (7) and D(9) and have the following structures: Drebyssogenin F (5) = 11-O-acetyl-12-O-(α-hydroxyisovaleryl)-drevogenin P, drebyssogenin G (14) = 11-O-acetyl-12-O-isovaleryl-drevogenin D, drebyssogenin J (15) = 11, 12-di-O-acetyl-drevogenin D. Drebyssogenin K is a mixture of K1 (16) and K2 (17), the mono-O-tiglyl and mono-O-isovaleryl derivatives of drevogenin D respectively, with as yet undetermined position of the acyl residues. The drebyssosides 1, 2 and 3 are glycosides of trisaccharides. Drebyssoside 1 (2) is pachybiosyl-cymarosyl-drevogenin A, drebyssoside 2 (3) asclepobiosyl-cymarosyl-drevogenin A and drebyssoside 3 (6) pachybiosyl-cymarosyl-drebyssogenin F. Drebyssoside 4 is a mixture of at least two components and contains the same aglycones and the same sugar units as the drebyssosides 1 and 3, but is different from them. The full structure of the two sugars (drebyssobiose (25) and sugar T (24)) has not been determined; it is only shown that both are disaccharides which contain 3-O-methyl-6-deoxy-allose linked to a 2-deoxyhexose.
Additional Material:
10 Ill.
Type of Medium:
Electronic Resource
URL:
http://dx.doi.org/10.1002/hlca.19680510114
