ISSN:
0018-019X
Keywords:
Chemistry
;
Organic Chemistry
Source:
Wiley InterScience Backfile Collection 1832-2000
Topics:
Chemistry and Pharmacology
Notes:
[2,3-13C2]Pyruvic acid (7) was synthesized and administered to cultures of Pseudomonas syringae pv tabaci. C(2) and C(3) of 7 were incorporated as an intact unit into the β-lactam moiety of tabtoxin (1). The result suggests that the biosynthesis of 1 is proceeding in part along the lysine pathway. The labelling pattern in 1 and an incorporation experiment with α,α′-dideuterated (±)-2,6-diaminopimelic acid (19) indicate that the branching in the biosynthesis of 1 occurs before lysine is formed.
Additional Material:
2 Ill.
Type of Medium:
Electronic Resource
URL:
http://dx.doi.org/10.1002/hlca.19900730228