ISSN:
0018-019X
Keywords:
Chemistry
;
Organic Chemistry
Source:
Wiley InterScience Backfile Collection 1832-2000
Topics:
Chemistry and Pharmacology
Notes:
The oxidation reactions of a series of quinoxaline derivatives, using KMnO4 in the presence or absence of NaOH, are described. Neutral oxidation of 2-chloro- and 2, 3-dichloroquinoxalines 2-4 afforded the corresponding chloro- and dichloropyrazinedicarboxylic acids 13 and 14 in good yield. On the other hand, oxidation of quinoxalin-2(1H)-one and 1, 4-dihydroquinoxaline-2, 3-dione derivatives in alkaline medium gave different products, with the quinoxalin-2(1H)-one (5) forming 1, 4-dihydroquinoxaline-2, 3-dione (9), while various substituted quinoxalin-2, 3-dione derivatives (see 9-11) gave a new type of dimeric products. The structural assignments for the new compounds were based on spectroscopic data.
Type of Medium:
Electronic Resource
URL:
http://dx.doi.org/10.1002/hlca.19940770610
