ISSN:
0018-019X
Keywords:
Chemistry
;
Organic Chemistry
Source:
Wiley InterScience Backfile Collection 1832-2000
Topics:
Chemistry and Pharmacology
Notes:
The synthesis of benzazepine analogues of the opium alkaloid noscapine (1) is described. The benzazepines 2 and 3 were prepared starting from nornarceine ethyl ester (4; readily available from 1) in several steps. X-Ray analysis of compound 2 revealed that it is not a diastereosisomer mixture but a racemate of the threo-form and thus has the same configuration as 1.
Type of Medium:
Electronic Resource
URL:
http://dx.doi.org/10.1002/hlca.19940770615