ISSN:
0018-019X
Keywords:
Chemistry
;
Organic Chemistry
Source:
Wiley InterScience Backfile Collection 1832-2000
Topics:
Chemistry and Pharmacology
Notes:
The synthesis of 4-acetylcolchicine (1) by Swern dehydrogenation of the corresponding mixture of 4-[(R)-1-hydroxyethyl]- and 4-[(S)-1-hydroxyethyl]colchicine (3a and 3b, respectively) is described (cf. Scheme). The X-ray analysis of 1 (cf. Fig.), crystallized from MeOH, showed the presence of MeOH in the crystals.
Additional Material:
1 Ill.
Type of Medium:
Electronic Resource
URL:
http://dx.doi.org/10.1002/hlca.19960790120