ISSN:
0018-019X
Keywords:
Chemistry
;
Organic Chemistry
Source:
Wiley InterScience Backfile Collection 1832-2000
Topics:
Chemistry and Pharmacology
Notes:
α-Bromination of 9-acetoxy rubanone 2 and subsequent reaction with secondary amines gave bicyclic α-amino ketones as a kinetic product and a 4-oxa-1-azatwistan-2-one 6 under thermodynamic conditions. This two-step procedure represents a concise 1,2-carbonyl transposition and provides a short route to lactam alkaloids.
Additional Material:
2 Ill.
Type of Medium:
Electronic Resource
URL:
http://dx.doi.org/10.1002/hlca.19980810551