ISSN:
0021-8383
Keywords:
Chemistry
;
Organic Chemistry
Source:
Wiley InterScience Backfile Collection 1832-2000
Topics:
Chemistry and Pharmacology
Notes:
An improved and efficient method for the preparation of the title compounds 3 is described. Thus, quinoxalinecarboxamide 1,4-dioxides 3 are synthesized in high yields by reaction of benzofuroxan 1 with acetoacetamides 2 in the presence of catalytic amounts of calcium salts and ethanolamine. The reaction is assumed to involve a chelate mechanism with 4 as intermediate. Side reactions are studied by means of HPLC and TLC.
Additional Material:
4 Tab.
Type of Medium:
Electronic Resource
URL:
http://dx.doi.org/10.1002/prac.19893310506