ISSN:
0894-3230
Keywords:
Organic Chemistry
;
Physical Chemistry
Source:
Wiley InterScience Backfile Collection 1832-2000
Topics:
Chemistry and Pharmacology
,
Physics
Notes:
The recent attempts to evaluate the stereoelectronic effects at carboxyl oxygen using Kemp's triacid derivatives are reviewed. Contexts include metal-ion chelation, acidity measurements, intramolecular general base catalysis and nucleophilic substitution. These give a range of 0-8 kcal/mol for the effects, and leave the issue open for more incisive experiments.
Additional Material:
1 Tab.
Type of Medium:
Electronic Resource
URL:
http://dx.doi.org/10.1002/poc.610051010